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GESTATIONAL TROPHOBLASTIC NEOPLASIA
Clinical Obstetrics and Gynecology, 1974This review covers the development of chemotherapeutic treatment during the past 25 years for gestational trophoblastic neoplasia; there is now a cure rate of 80% of the cases of hydatiform mole invasive mole and choriocarcinoma. The clinician pathologist investigator will have the prime role in future breakthroughs as he has had in the preceeding ...
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Gestational trophoblastic neoplasia
Seminars in Oncology Nursing, 1990Gestational trophoblastic neoplasia (GTN) constitutes a spectrum of benign and malignant diseases that are associated with conception. The majority of patients with a benign GTN (hydatidiform mole) spontaneously enter remission after evacuation; however, 15% to 20% will develop a malignant form of GTN.
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Gestational trophoblastic neoplasia
2011Abstract Arising from the cells of conception, gestational trophoblastic disease (GTD) forms a spectrum of disorders from the premalignant complete and partial hydatidiform moles through to the malignant invasive mole, choriocarcinoma and very rare placental site trophoblastic tumours (PSTT).
Philip Savage, Michael J. Seckl
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Gestational Trophoblastic Neoplasia
Hospital Practice, 1972The chorionic gonadotropin titer now makes it possible to identify early those postmolar patients who are likely to progress to choriocarcinoma, thereby opening the way to definitive treatment of this highly lethal condition. Complete and sustained remission can now be achieved in 90% of patients in whom appropriate chemotherapy is begun within four ...
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Sex assignment in gestational trophoblastic neoplasia
American Journal of Obstetrics and Gynecology, 1984A retrospective survey was performed in 205 cases of gestational trophoblastic neoplasia with the use of routine tissue sections and quinacrine stain after hydrolysis and pronase pretreatment. The method allows scoring of nuclei simultaneously for either Y chromatin or X chromatin (Barr body) and has proved to be a valid test for sex assignment in ...
J R, Davis +3 more
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Immunological parameters in gestational trophoblastic neoplasia
Journal of Reproductive Immunology, 1980Immunological function were studied in 22 patients with hydatidiform mole and 29 patients with malignant trophoblastic disease before and after treatment; normal pregnant and post-pregnant women served as controls. The only significant abnormality in hydatidiform mole was a low granulocyte chemotaxis before evacuation.
Lawton, JWM, Ho, PC, Mak, LW, Ma, HK
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Current Management of Gestational Trophoblastic Neoplasia
Hematology/Oncology Clinics of North America, 2012Gestational trophoblastic neoplasms are malignant lesions that arise from placental villous and extravillous trophoblast. Four clinicopathologic conditions make up this entity: invasive mole (IM), choriocarcinoma (CCA), placental-site trophoblastic tumor (PSTT), and epithelioid trophoblastic tumor (ETT).
Donald Peter, Goldstein +1 more
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Gestational Trophoblastic Neoplasia
2015The pathologic classification and histologic findings of gestational trophoblastic neoplasia are discussed.
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Gestational trophoblastic neoplasia.
Current opinion in obstetrics & gynecology, 1991In many areas, GTN have become a success story in the field of oncology. It is well known that pregnancies with hydatidiform moles are high risk and carry the potential for the development of malignant forms of GTN. Monitoring with hCG levels has become accepted as the model for a sensitive and specific serum tumor marker.
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Current Evidence on Immunotherapy for Gestational Trophoblastic Neoplasia (GTN)
Cancers, 2022Alice Bergamini +2 more
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