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Gestational trophoblastic neoplasia
Seminars in Oncology Nursing, 1990Gestational trophoblastic neoplasia (GTN) constitutes a spectrum of benign and malignant diseases that are associated with conception. The majority of patients with a benign GTN (hydatidiform mole) spontaneously enter remission after evacuation; however, 15% to 20% will develop a malignant form of GTN.
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Gestational trophoblastic neoplasia
2011Abstract Arising from the cells of conception, gestational trophoblastic disease (GTD) forms a spectrum of disorders from the premalignant complete and partial hydatidiform moles through to the malignant invasive mole, choriocarcinoma and very rare placental site trophoblastic tumours (PSTT).
Philip Savage, Michael J. Seckl
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Gestational Trophoblastic Neoplasia
Hospital Practice, 1972The chorionic gonadotropin titer now makes it possible to identify early those postmolar patients who are likely to progress to choriocarcinoma, thereby opening the way to definitive treatment of this highly lethal condition. Complete and sustained remission can now be achieved in 90% of patients in whom appropriate chemotherapy is begun within four ...
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Gestational Trophoblastic Neoplasia
2015The pathologic classification and histologic findings of gestational trophoblastic neoplasia are discussed.
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Gestational trophoblastic neoplasia: an update
Current Oncology Reports, 2008Gestational trophoblastic neoplasia (GTN) includes invasive mole, choriocarcinoma, and placental site trophoblastic tumors. The overall cure rate in treating these tumors currently exceeds 90%. Thorough evaluation and staging allow selection of appropriate therapy that maximizes chances for cure while minimizing toxicity.
Jacqueline M, Morgan, John R, Lurain
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Management of Gestational Trophoblastic Neoplasia
Seminars in Oncology, 2009Molar pregnancy and gestational trophoblastic neoplasms (GTN) comprise a group of interrelated diseases with a varying degree of aggressiveness. Complete and partial molar pregnancy, invasive mole, placental site trophoblastic tumor (PSTT), and choriocarcinoma cover the spectrum of GTN.
Neil S, Horowitz +2 more
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Radiology of gestational trophoblastic neoplasia
Clinical Radiology, 2006Gestational trophoblastic neoplasia (GTN) encompasses a broad spectrum of placental lesions from the pre-malignant hydatidiform mole (complete and partial) through to the malignant invasive mole, choriocarcinoma and rare placental site trophoblastic tumour (PSTT). Ultrasound remains the radiological investigation of choice for initial diagnosis, and it
S D, Allen +4 more
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HYPERTHYROIDISM IN GESTATIONAL TROPHOBLASTIC NEOPLASIA
Clinical Endocrinology, 1981SUMMARYThe thyroid status of twenty‐seven African patients with gestational trophoblastic neoplasia (GTN) was studied. Fifteen patients were found to be biochemically hyperthyroid (eight patients with choriocarcinoma; seven with hydatidiform mole). Of these fifteen patients, nine were clinically thyrotoxic.
R J, Norman +5 more
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Risk factors for Gestational Trophoblastic Neoplasia
Gynecologic Oncology, 1985A case-control study to determine the gynecologic and reproductive risk factors for gestational trophoblastic neoplasia was conducted in the Baltimore Metropolitan Area. All cases (N = 190) that were pathologically diagnosed from 1975 to 1982 as hydatidiform mole, invasive mole, or choriocarcinoma were ascertained. Slides were independently reviewed by
M L, Messerli +4 more
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Gestational trophoblastic neoplasia.
Current opinion in obstetrics & gynecology, 1991In many areas, GTN have become a success story in the field of oncology. It is well known that pregnancies with hydatidiform moles are high risk and carry the potential for the development of malignant forms of GTN. Monitoring with hCG levels has become accepted as the model for a sensitive and specific serum tumor marker.
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