Results 161 to 170 of about 2,858 (200)

Gestational Trophoblastic Neoplasia

Obstetrics & Gynecology, 2008
To report the results of treatment of gestational trophoblastic neoplasia (GTN) at the John I. Brewer Trophoblastic Disease Center over the past 28 years, compare the outcomes to those from the first 16 years, and analyze factors affecting response to treatment and survival.We reviewed the records of 408 patients with GTN (excluding placental-site ...
Anna V, Hoekstra, John R, Lurain, Alfred W, Rademaker, Julian C, Schink   +3 more
  +5 more sources

Single-dose methotrexate regimen in the treatment of low-risk gestational trophoblastic neoplasia

American Journal of Obstetrics and Gynecology, 2006
Objective: The objective of the study was to evaluate the effectiveness of single-dose methotrexate in women with low-risk gestational trophoblastic neoplasia.
Karen K L Chan, Ka Yu Tse, Hextan Y S Ngan   +2 more
exaly   +2 more sources

Gestational Trophoblastic Neoplasia

Obstetrics and Gynecology Clinics of North America, 2012
Trophoblastic neoplasms are a truly fascinating set of diseases that arise from a failed gestation. A molar pregnancy is an allograft of fetal tissue typically containing only paternal chromosomes that may invade the maternal decidua following a failed gestation that may have arisen up to decades earlier.
R, Osborne, J, Dodge
openaire   +2 more sources

Gestational trophoblastic neoplasia: an update

Current Oncology Reports, 2008
Gestational trophoblastic neoplasia (GTN) includes invasive mole, choriocarcinoma, and placental site trophoblastic tumors. The overall cure rate in treating these tumors currently exceeds 90%. Thorough evaluation and staging allow selection of appropriate therapy that maximizes chances for cure while minimizing toxicity.
Jacqueline M, Morgan, John R, Lurain
openaire   +2 more sources

Management of Gestational Trophoblastic Neoplasia

Seminars in Oncology, 2009
Molar pregnancy and gestational trophoblastic neoplasms (GTN) comprise a group of interrelated diseases with a varying degree of aggressiveness. Complete and partial molar pregnancy, invasive mole, placental site trophoblastic tumor (PSTT), and choriocarcinoma cover the spectrum of GTN.
Neil S, Horowitz, Donald P, Goldstein, Ross S, Berkowitz   +2 more
openaire   +2 more sources

Radiology of gestational trophoblastic neoplasia

Clinical Radiology, 2006
Gestational trophoblastic neoplasia (GTN) encompasses a broad spectrum of placental lesions from the pre-malignant hydatidiform mole (complete and partial) through to the malignant invasive mole, choriocarcinoma and rare placental site trophoblastic tumour (PSTT). Ultrasound remains the radiological investigation of choice for initial diagnosis, and it
S D, Allen, A K, Lim, M J, Seckl, D M, Blunt, A W, Mitchell   +4 more
openaire   +2 more sources

HYPERTHYROIDISM IN GESTATIONAL TROPHOBLASTIC NEOPLASIA

Clinical Endocrinology, 1981
SUMMARYThe thyroid status of twenty‐seven African patients with gestational trophoblastic neoplasia (GTN) was studied. Fifteen patients were found to be biochemically hyperthyroid (eight patients with choriocarcinoma; seven with hydatidiform mole). Of these fifteen patients, nine were clinically thyrotoxic.
R J, Norman, R W, Green-Thompson, I, Jialal, W P, Soutter, N L, Pillay, S M, Joubert   +5 more
openaire   +2 more sources

Risk factors for Gestational Trophoblastic Neoplasia

Gynecologic Oncology, 1985
A case-control study to determine the gynecologic and reproductive risk factors for gestational trophoblastic neoplasia was conducted in the Baltimore Metropolitan Area. All cases (N = 190) that were pathologically diagnosed from 1975 to 1982 as hydatidiform mole, invasive mole, or choriocarcinoma were ascertained. Slides were independently reviewed by
M L, Messerli, A M, Lilienfeld, T, Parmley, J D, Woodruff, N B, Rosenshein   +4 more
openaire   +2 more sources

GESTATIONAL TROPHOBLASTIC NEOPLASIA

Clinical Obstetrics and Gynecology, 1974
This review covers the development of chemotherapeutic treatment during the past 25 years for gestational trophoblastic neoplasia; there is now a cure rate of 80% of the cases of hydatiform mole invasive mole and choriocarcinoma. The clinician pathologist investigator will have the prime role in future breakthroughs as he has had in the preceeding ...
openaire   +2 more sources

Gestational trophoblastic neoplasia

Seminars in Oncology Nursing, 1990
Gestational trophoblastic neoplasia (GTN) constitutes a spectrum of benign and malignant diseases that are associated with conception. The majority of patients with a benign GTN (hydatidiform mole) spontaneously enter remission after evacuation; however, 15% to 20% will develop a malignant form of GTN.
openaire   +2 more sources