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Management of Gestational Trophoblastic Neoplasia
Seminars in Oncology, 2009Molar pregnancy and gestational trophoblastic neoplasms (GTN) comprise a group of interrelated diseases with a varying degree of aggressiveness. Complete and partial molar pregnancy, invasive mole, placental site trophoblastic tumor (PSTT), and choriocarcinoma cover the spectrum of GTN.
Neil S, Horowitz +2 more
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Radiology of gestational trophoblastic neoplasia
Clinical Radiology, 2006Gestational trophoblastic neoplasia (GTN) encompasses a broad spectrum of placental lesions from the pre-malignant hydatidiform mole (complete and partial) through to the malignant invasive mole, choriocarcinoma and rare placental site trophoblastic tumour (PSTT). Ultrasound remains the radiological investigation of choice for initial diagnosis, and it
S D, Allen +4 more
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HYPERTHYROIDISM IN GESTATIONAL TROPHOBLASTIC NEOPLASIA
Clinical Endocrinology, 1981SUMMARYThe thyroid status of twenty‐seven African patients with gestational trophoblastic neoplasia (GTN) was studied. Fifteen patients were found to be biochemically hyperthyroid (eight patients with choriocarcinoma; seven with hydatidiform mole). Of these fifteen patients, nine were clinically thyrotoxic.
R J, Norman +5 more
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GESTATIONAL TROPHOBLASTIC NEOPLASIA
Clinical Obstetrics and Gynecology, 1974This review covers the development of chemotherapeutic treatment during the past 25 years for gestational trophoblastic neoplasia; there is now a cure rate of 80% of the cases of hydatiform mole invasive mole and choriocarcinoma. The clinician pathologist investigator will have the prime role in future breakthroughs as he has had in the preceeding ...
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Gestational trophoblastic neoplasia
Seminars in Oncology Nursing, 1990Gestational trophoblastic neoplasia (GTN) constitutes a spectrum of benign and malignant diseases that are associated with conception. The majority of patients with a benign GTN (hydatidiform mole) spontaneously enter remission after evacuation; however, 15% to 20% will develop a malignant form of GTN.
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Risk factors for Gestational Trophoblastic Neoplasia
Gynecologic Oncology, 1985A case-control study to determine the gynecologic and reproductive risk factors for gestational trophoblastic neoplasia was conducted in the Baltimore Metropolitan Area. All cases (N = 190) that were pathologically diagnosed from 1975 to 1982 as hydatidiform mole, invasive mole, or choriocarcinoma were ascertained. Slides were independently reviewed by
M L, Messerli +4 more
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Role of Hysterectomy in Gestational Trophoblastic Neoplasia
Indian Journal of Surgical Oncology, 2021Hysterectomy has a limited role in the management of gestational trophoblastic neoplasia because of the high effectiveness of chemotherapy and the young age of patients. In selected patients, it is believed to help in reducing the number of chemotherapy cycles, overcoming chemo-resistance, and treating acute haemorrhagic events. The present study aimed
C. K. Ramesan +6 more
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Gestational trophoblastic neoplasia
2011Abstract Arising from the cells of conception, gestational trophoblastic disease (GTD) forms a spectrum of disorders from the premalignant complete and partial hydatidiform moles through to the malignant invasive mole, choriocarcinoma and very rare placental site trophoblastic tumours (PSTT).
Philip Savage, Michael J. Seckl
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Gestational Trophoblastic Neoplasia
Hospital Practice, 1972The chorionic gonadotropin titer now makes it possible to identify early those postmolar patients who are likely to progress to choriocarcinoma, thereby opening the way to definitive treatment of this highly lethal condition. Complete and sustained remission can now be achieved in 90% of patients in whom appropriate chemotherapy is begun within four ...
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Current Management of Gestational Trophoblastic Neoplasia
Hematology/Oncology Clinics of North America, 2012Gestational trophoblastic neoplasms are malignant lesions that arise from placental villous and extravillous trophoblast. Four clinicopathologic conditions make up this entity: invasive mole (IM), choriocarcinoma (CCA), placental-site trophoblastic tumor (PSTT), and epithelioid trophoblastic tumor (ETT).
Donald Peter, Goldstein +1 more
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