Results 51 to 60 of about 2,811 (122)

Thyroid antibody positivity in pregnancy is associated with altered reproductive hormone concentrations and placental growth in Lewis rats

open access: yesThe Journal of Physiology, Volume 604, Issue 17, Page 7464-7489, 1 September 2026.
Abstract figure legend Thyroid antibody positivity (TAb+) in pregnancy is associated with adverse pregnancy outcomes, but the mechanisms are unclear. This study developed a rodent model of TAb+ in pregnancy, induced prior to mating so that TAb+ exposure occurred throughout the pregnancy. TAb+ did not alter thyroid hormone concentrations and had minimal
Rebecca L. Brady   +11 more
wiley   +1 more source

Actinomycin Derivatives: Structural Diversification and Biological Activities

open access: yesChemMedChem, Volume 21, Issue 15, 14 August 2026.
Actinomycins are chromopeptide antibiotics exhibiting remarkable structural diversity and broad bioactivity. This review traces their development from naturally occurring D‐, X‐, A‐, G‐, Y‐, and Z‐type analogs to precursor‐directed, synthetic, and semisynthetic derivatives.
Özge Can, Erdal Bedir
wiley   +1 more source

Is Doppler ultrasound useful for evaluating gestational trophoblastic disease?

open access: yesClinics
Doppler ultrasound is a non-invasive method for evaluating vascularization and is widely used in clinical practice. Gestational trophoblastic neoplasia includes a group of highly vascularized malignancies derived from placental cells.
Lawrence H. Lin   +4 more
doaj   +1 more source

Fatores de risco para doença trofoblástica gestacional persistente Risk factors for persistent gestational trophoblastic disease

open access: yesRevista Brasileira de Ginecologia e Obstetrícia, 2005
OBJETIVOS: avaliar o impacto dos fatores de riscos na evolução para doença trofoblástica gestacional persistente (DTGP) e selecionar grupos de pacientes para seguimento intensivo e os que poderiam se beneficiar de quimioterapia profilática.
Daniel Guimarães Tiezzi   +4 more
doaj   +1 more source

Possible risk for gestational trophoblastic neoplasm in perimenopause and menopause [PDF]

open access: yesSanamed, 2011
Gestational Trophoblastic Neoplasms (GTN) are group of diseases which are known as fertilization disorders and may appear as Complete hydatidiform mole, Mole partialis, Invasive mole, Placental site trophoblastic tumor, Choriocarcinoma. Malignant disease
Nikolić Branka   +5 more
doaj  

Comparison of ?-HCG Regression Curve in Molar Pregnancy and Gestational Trophoblastic Neoplasms

open access: yesپزشکی بالینی ابن سینا, 2011
Introduction & Objective: All cases of gestational trophoblastic tumors are curable if exact diagnosis and early treatment is done. The serum level of βHCG is a sensitive marker of the disease.
Fatemeh Homaee   +4 more
doaj  

Whole genome uniparental isodisomy detected using single nucleotide polymorphism (SNP) microarray in molar pregnancy: a case report

open access: yesMolecular Cytogenetics
Background Gestational trophoblastic neoplasms consist of complete and partial hydatidiform moles, both of which are considered aberrant conceptuses.
Onyinye O. Okonkwo   +6 more
doaj   +1 more source

Molecular genetic study of triploidy and the hydatidiform mole in pregnancy loss: analysis of 10,000 consecutive cases

open access: yesВавиловский журнал генетики и селекции
Approximately 10–15 % of clinically recognized pregnancies result in miscarriage, with chromosomal abnormalities identified in about 50 % of early pregnancy losses (PL).
V. P. Pushkarev   +4 more
doaj   +1 more source

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