Results 51 to 60 of about 240,583 (210)
Higher pretreatment β‐hCG, greater tumor burden, higher FIGO stage/score, and choriocarcinoma were associated with higher chemoresistance risk in gestational trophoblastic neoplasia. In exploratory network analyses, etoposide‐containing regimens showed lower predicted chemoresistance.
Ying‐Ying Xue +7 more
wiley +1 more source
ABSTRACT Aims This study evaluated the clinical utility of circulating miR‐342‐3p for diagnosing gestational diabetes mellitus (GDM) and predicting adverse perinatal outcomes (APOs). Methods A retrospective cohort of 261 GDM women (the GDM group) and 261 propensity score‐matched healthy controls (the Normal group) was analyzed.
Kangjun Yu, Sanqiang Niu, Hai Liang
wiley +1 more source
Gestational Trophoblastic Disease
The diagnosis of gestational trophoblastic disease has witnessed revolutionary changes with improved availability of immunohistochemistry and genotyping as valuable adjuncts.
Wang, RW, Cheung, ANY
core +1 more source
Periodontitis and Adverse Pregnancy Outcomes: Mechanistic Evidence
This narrative review aims to describe mechanisms linking periodontal diseases in pregnancy with adverse pregnancy outcomes. ABSTRACT Periodontal diseases, including both gingivitis and periodontitis, occur commonly among pregnant individuals. Both gingivitis and periodontitis are associated with adverse pregnancy outcomes (APOs) such as early ...
Gregory C. Valentine +4 more
wiley +1 more source
Abstract Pregnancy requires the coordinated maternal reorganization of lipid and endocrine pathways to sustain fetal growth and anticipate neonatal nutrition. Leptin, produced by adipose tissue and the placenta, acts as an integrative signal linking maternal energy status with trophoblast function and vascular adaptation, while cholesterol provides ...
Julio Flores +4 more
wiley +1 more source
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor +4 more
wiley +1 more source
High risk gestational trophoblastic diseases: Diagnosis and primary management with EMACO chemotherapy [PDF]
Gestational trophoblastic disease (GTD) is characterized by abnormal proliferation of pregnancy associated trophoblastic tissue with malignant potential.
Kadam R. Priyanka, Dave S. Pariseema
core +1 more source
Objective: To determine the frequency of gestational trophoblastic diseases and gestational tropho- blastic neoplasm, its risk factors and prognosis. Methods: This was a descriptive, cross-sectional study conducted at Civil Hospital, Karachi from March 2015 to September 2015.
Shakira Perveen +2 more
openaire +2 more sources
Abstract figure legend The fetal–maternal interface organ‐on‐chip was used to investigate the ascending infection of Gardnerella spp. across the decidua (DEC), chorion trophoblast (CTC), amnion mesenchymal (AMC) and amnion epithelial (AEC) compartments over 48 h.
Mariana de Castro Silva +7 more
wiley +1 more source
Gestational trophoblastic disease (GTD) includes hydatidiform mole (HM), which can develop persistent gestational trophoblastic neoplasia requiring chemotherapy; choriocarcinoma, which is a frankly malignant tumor; placental site trophoblastic tumor; and
Chan, DCW +7 more
core +1 more source

