Results 101 to 110 of about 87,448 (313)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Gesture-based Object Recognition using Histograms of Guiding Strokes

open access: yes, 2012
Sadeghipour A, Morency L-P, Kopp S. Gesture-based Object Recognition using Histograms of Guiding Strokes. In: Bowden R, Collomosse J, Mikolajczyk K, eds. Proceedings of the British Machine Vision Conference.
Kopp, Stefan ; https://orcid.org/   +5 more
core  

Intelligent Contactless Gesture Recognition Using WLAN Physical Layer Information

open access: yesIEEE Access, 2019
Contactless gesture recognition is an emerging interactive technique in ubiquitous and mobile computing. It combines the linguistics with the wireless signals to analyze, judge, and integrate human gestures by the usage of intelligent algorithms.
Shujie Ren   +5 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Integrating Gesture Meaning and Verbal Meaning for German Verbs of Motion: Theory and Simulation

open access: yes, 2013
Bergmann K, Hahn F, Kopp S, Rieser H, Röpke I. Integrating Gesture Meaning and Verbal Meaning for German Verbs of Motion: Theory and Simulation. In: Proceedings of the Tilburg Gesture Research Meeting (TiGeR 2013).
Hahn, Florian   +4 more
core  

Gesture Processing as Grounded Motor Cognition - Towards a Computational Model

open access: yes, 2012
Sadeghipour A, Kopp S. Gesture Processing as Grounded Motor Cognition - Towards a Computational Model. In: Rahbar-Shamskar A, ed. 4th International Conference of Cognitive Science (ICCS 2011). Procedia - Social and Behavioral Sciences. Vol 32.
Kopp, Stefan ; https://orcid.org/   +3 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Domestic dogs use contextual information and tone of voice when following a human pointing gesture [PDF]

open access: yes, 2011
Domestic dogs are skillful at using the human pointing gesture. In this study we investigated whether dogs take contextual information into account when following pointing gestures, specifically, whether they follow human pointing gestures more readily ...
Grassmann, Susanne   +16 more
core   +1 more source

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