Results 131 to 140 of about 394,964 (308)

Praxis and Gesture Recognition

open access: yes, 2016
Most of the developed societies are experiencing an aging trend of theirpopulation. Aging is correlated with cognitive impairment such as dementia and its mostcommon type: Alzheimer's disease. So, there is an urgent need to develop technological toolsto help doctors to do early and precise diagnoses of cognitive decline.Inability to correctly perform ...
Negin, Farhood   +4 more
openaire   +3 more sources

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

High Five: Improving Gesture Recognition by Embracing Uncertainty [PDF]

open access: yesarXiv, 2017
Sensors on mobile devices---accelerometers, gyroscopes, pressure meters, and GPS---invite new applications in gesture recognition, gaming, and fitness tracking. However, programming them remains challenging because human gestures captured by sensors are noisy.
arxiv  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Multi-modal gesture recognition with voting-based dynamic time warping

open access: yesInternational Journal of Advanced Robotic Systems, 2019
Gesture recognition has remained a challenging problem in the fields of human robot interaction. With the development of depth sensors such as Kinect, different modalities become available for gesture recognition while its advantages have not been fully ...
Yiqun Kuang   +4 more
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Interplay of integrins and selectins in metastasis

open access: yesMolecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva   +2 more
wiley   +1 more source

Handwritten Gesture Recognition for Gesture Keyboard

open access: yes, 2006
Gesture Keyboard (GKB) is a novel method of text input for syllabic scripts whose success and acceptance is critically dependent on the reliability of handwritten gesture recognition. In this paper, we describe the solution we have developed for the Devanagari Gesture Keyboard.
Balaji, R.   +3 more
openaire   +2 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

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