Results 121 to 130 of about 147,929 (284)
Chronic Kidney Disease (CKD) is defined as the presence of markers of kidney damage or of estimated glomerular filtration rate (eGFR)
Simeon A Adebisi
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Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao +8 more
wiley +1 more source
What's New? Hypoxic regions and inflammatory Th17 cells in the tumor environment are both associated with poor prognosis in cervical cancer. However, synergistic mechanisms between hypoxia and Th17 cells remain elusive. This study demonstrated Th17–hypoxia‐driven mechanisms underlying cervical cancer progression.
Selina Gies +12 more
wiley +1 more source
Abstract Background Children with intestinal failure are at risk for kidney dysfunction; however, the contributing factors are not well established. We aimed to describe risk factors associated with glomerular and tubular renal dysfunction in children with intestinal failure.
Amanda M. Braga da Mata +7 more
wiley +1 more source
Objectives The femoropopliteal (FP) artery is the most frequently revascularized segment in peripheral artery disease (PAD), followed by the iliac segment. Wall shear stress (WSS) is a key local factor implicated in both atherosclerotic plaque formation and restenosis after angioplasty.
Jan Lukas Prüser +5 more
wiley +1 more source
ABSTRACT Purpose Blood T1 is a key parameter for hemodynamic quantification in both non‐contrast‐ and contrast‐enhanced imaging. Individual vessel T1 has been measured using a modified Look–Locker scheme with multi‐shot EPI or FLASH in high spatial resolution, requiring ∼1 min.
Zechen Xu, Feng Xu, Qin Qin, Dan Zhu
wiley +1 more source
ABSTRACT Purpose To demonstrate that a recently reported bright ferritin magnetic resonance imaging (MRI) platform can track transplanted human pluripotent stem cell (hPSC)‐derived cardiomyocytes (hPSC‐CMs) longitudinally and on‐demand in the rat heart.
Keyu Zhuang +12 more
wiley +1 more source
ABSTRACT Introduction Maintenance of bladder filling and urinary storage at low intravesical pressures is fundamental to minimizing risk to the upper urinary tract. Bladder compliance describes the relationship between the bladder volume and the change in detrusor pressure during the filling phase of urodynamics.
Eric Rovner +5 more
wiley +1 more source
Lengnan Xu,1 Chen Yu,1 Aiqun Chen,1 Chuanbao Li,2 Yonghui Mao1 1Department of Nephrology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, People’s Republic of China ...
Xu L, Yu C, Chen A, Li C, Mao Y
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