Results 151 to 160 of about 147,929 (284)

Focal therapy using a novel cooled laser device for prostate cancer: early trial results

open access: yesBJU International, EarlyView.
Objectives To determine the short‐term oncological results and safety of the ProFocal Laser Therapy for Prostate Tissue Ablation (PFLT‐PC) trial, the first phase II clinical trial of ProFocal® (Medlogical Innovations, Sydney, Australia), a novel, cooled laser focal therapy (cLFT) device for prostate cancer (PCa) treatment. Patients and Methods Men with
Jonathan Kam   +17 more
wiley   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Apparent diffusion coefficient of kidneys with non-contrast magnetic resonance angiography for functional and anatomical assessment in renal artery stenosis. [PDF]

open access: yesWorld J Methodol
Lal H   +9 more
europepmc   +1 more source

TREM2 in Macrophages Promotes Renal Fibrosis via Activation of β‐Catenin Signalling Pathway in Obstructive Nephropathy

open access: yesCell Proliferation, EarlyView.
Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) promotes obstructive nephropathy progression by activating the β‐catenin signalling pathway, driving M2 macrophage polarisation, migration and fibrogenic gene expression. targeted inhibition of TREM2 thus represents a promising novel strategy against renal fibrosis.
Jia Wei   +7 more
wiley   +1 more source

Triptolide capsule enables proteinuria reduction and renal stabilization in advanced alport syndrome beyond standard therapy

open access: yes
Rheumatology &Autoimmunity, EarlyView.
Zhuo‐ran Song   +4 more
wiley   +1 more source

Type 2 diabetes subphenotypes are associated with differential outcomes after metabolic and bariatric surgery: An international multicentre retrospective cohort study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Type 2 diabetes (T2D) is characterized by its clinical heterogeneity. Newly described T2D subphenotypes, each with distinct metabolic and co‐morbidity risk profiles, may enable a more personalized care. This study examined whether these subphenotypes can predict outcomes in patients undergoing metabolic and bariatric surgery (MBS ...
Adisa Poljo   +18 more
wiley   +1 more source

Association Between Donor Kidney Function and Post-Transplant Graft Function in Deceased-Donor Kidney Transplantation. [PDF]

open access: yesJ Clin Med
Pezeshk AS   +13 more
europepmc   +1 more source

Baseline and 4‐year associations between prediabetes and kidney impairment: Insights from the ILERVAS cohort

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Prediabetes is a prevalent condition associated with increased cardiovascular and renal risk. However, the long‐term impact of haemoglobin A1c (HbA1c) within the range defined as prediabetes on kidney function remains unclear. This study aimed to evaluate the association between prediabetes and renal function (estimated glomerular ...
Aitziber Izarra   +23 more
wiley   +1 more source

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