Results 61 to 70 of about 103,707 (261)

Extended Criteria Donors in Living Kidney Transplantation Including Donor Age, Smoking, Hypertension and BMI

Therapeutics and Clinical Risk Management, 2020
Henning Plage,1 Poline Pielka,1 Lutz Liefeldt,2 Klemens Budde,2 Jan Ebbing,3 Nesrin Sugünes,1 Kurt Miller,1 Hannes Cash,1 Anna Bichmann,4 Arne Sattler,5 Katja Kotsch,5 Frank Friedersdorff1 1Department of Urology, Charité – Universit ...
Plage H, Pielka P, Liefeldt L, Budde K, Ebbing J, Sugünes N, Miller K, Cash H, Bichmann A, Sattler A, Kotsch K, Friedersdorff F   +11 more
doaj  

On the Implementation of a European Space Traffic Management System - I. A White Paper [PDF]

, 2017
There are high expectations for a global commercial space travel market which is expected to turn into a multi-billion Euro business in the next two decades.
Tüllmann, Ralph, Fiedler, H., Berdermann, Jens, Arbinger, Christian, Schildknecht, Thomas, Arbinger, C., Fiedler, Hauke, Baskcomb, S., Klock, E., Baskcomb, Stuart, Klock, Erich, Tüllmann, R., Berdermann, J.   +12 more
core   +1 more source

Glomerular filtration rate (GFR).

, 2014
Distribution of GFR (ml/min/1.73 m2) among patients’ groups. Mean GFR was 45±11 ml/min/1.73 m2 (range: 10 to 58 ml/min/1.73 m2) and 78±14 ml/min/1.73 m2 (ranging from 61 to 136 ml/min/1.73 m2).
Carsten Bokemeyer (104368), Hans Klose (345834), Jan K. Hennigs (583778), Hans J. Baumann (583779), Elisabeth Griesch (583781), Lars Harbaum (583777), Nicole Lüneburg (583780), Ekkehard Grünig (148643)   +7 more
core   +1 more source

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

British Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza, Andrej Belancic, Jens Jordan, Alberto Esteban, Anna Oliveras, Ryan McNally, Panagiota Anyfanti, Jorie Versmissen, María S. Fernández‐Alfonso, Vasilios Kotsis, Thomas Weber, Alexandre Persu, Reinhold Kreutz   +12 more
wiley   +1 more source

Maternal glomerular filtration rate in pregnancy and fetal size. [PDF]

PLoS ONE, 2014
BACKGROUND: The relationship of maternal glomerular filtration rate (GFR) in pregnancy to fetal size needs to be better characterized as it impacts an ongoing debate about confounding effect of maternal GFR in investigations of important environmental ...
Nils-Halvdan Morken, Gregory S Travlos, Ralph E Wilson, Merete Eggesbø, Matthew P Longnecker   +4 more
doaj   +1 more source

Translational development of crisugabalin for neuropathic pain

British Journal of Clinical Pharmacology, EarlyView.
Abstract Crisugabalin (HSK16149) is a next‐generation α2δ ligand developed to preserve the mechanistic rationale of gabapentinoids while refining target engagement and exposure‐related tolerability constraints. We performed a translational review of molecular/structural studies, in vivo pharmacology and behavioural safety assessments, phase I clinical ...
Rafael Batista João, Jilly Octoria Tagore Chan, Luísa Mendes Araújo, André Batista João, Raquel Mattos Filgueiras, Paulo César Ragazzo   +5 more
wiley   +1 more source

Transcatheter Tricuspid Valve Replacement for Residual Tricuspid Regurgitation After TEER

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Residual or recurrent tricuspid regurgitation (TR) after prior transcatheter tricuspid edge‐to‐edge (T‐TEER) repair occurs in about 12% of patients within 1 year. Since surgical tricuspid valve repair or replacement is of high risk, treatment options remain scarce.
Fabian Voß, Philipp Mourikis, Fabian Nienhaus, Jafer Haschemi, Alexander Hoss, Tobias Zeus, Hanna Kowalski, Maximilian Spieker, Christian Jung, Patrick Horn, Hug Aubin, Artur Lichtenberg, Richard Truse, Malte Kelm, Amin Polzin   +14 more
wiley   +1 more source

Interventional Mitral Valve Edge‐to‐Edge Repair in Patients Above 85 Years of Age

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Mitral valve transcatheter‐edge‐to‐edge repair (M‐TEER) is routinely performed in patients with severe mitral regurgitation (MR) at high operative risk, frequently including elderly patients. Patients ≥ 85 years, however, are frequently excluded in clinical studies.
Florian Jürgens, Florian Schindhelm, Mohammed Abusharekh, Jürgen Kampf, Matthias Totzeck, Fadi Al‐Rashid, Peter Lüdike, Tienush Rassaf, Amir A. Mahabadi   +8 more
wiley   +1 more source

Measurement of Glomerular Filtration Rate Using Multiphasic Computed Tomography in Patients With Unilateral Renal Tumors: A Feasibility Study

Frontiers in Physiology, 2019
ObjectivesThis study was to assess the feasibility of a modified multiphasic CT scan protocol combined with homemade software measurements of glomerular filtration rate (CT-GFR) and explore the effect of renal tumor volume on the calculation of CT-GFR ...
Tingting Wang, Tingting Wang, Yi Xu, Wangyan Liu, Pengfei Shao, Qiang Lv, Guanyu Yang, Lijun Tang   +7 more
doaj   +1 more source

Measured GFR by Utilizing Population Pharmacokinetic Methods to Determine Iohexol Clearance

Kidney International Reports, 2020
Introduction: There is an increasing demand for accurately measured glomerular filtration rate (GFR). Iohexol serum clearance has become a new gold standard, but it is challenging when GFR is low and 24-hour sampling is required for accurate results. The
Anders Åsberg, Anna Bjerre, Runar Almaas, Sergio Luis-Lima, Ida Robertsen, Cathrin Lytomt Salvador, Esteban Porrini, George J. Schwartz, Anders Hartmann, Stein Bergan   +9 more
doaj   +1 more source