Results 71 to 80 of about 103,707 (261)
Maximum Allowable Contrast Dose and Risk of Acute Kidney Injury After Coronary Procedures
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Recent studies have questioned whether iodinated contrast is causally related to acute kidney injury (AKI). AIM We pursed a contemporary analysis to determine the impact of contrast dose on AKI following coronary procedures in an era of lower contrast doses and less nephrotoxic agents.
Harshita Gaba +6 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.Newly developed polymers with intrinsic microporosity (PIMs) were combined with benzo[c][1,2,5]thiadiazole (BTZ) to be used as visible light photocatalytic coatings on the Vortex Fluidic Device (VFD). The VFD's rapid rotation and continuous flow capabilities enhanced singlet oxygen and superoxide radical reactions, achieving a dramatic eightfold ...
Leonardo Amicosante +9 more
wiley +1 more source
PLoS ONE, 2013 Glomerular filtration rate (GFR) is an essential parameter of kidney function which can be measured by dynamic contrast enhanced magnetic resonance imaging (MRI-GFR) and transcutaneous approaches based on fluorescent tracer molecules (optical-GFR). In an
Frank G Zöllner +5 more
doaj +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Personalized dosing is particularly important for drugs with narrow therapeutic indices in geriatric patients, who exhibit substantial physiological variability and limited pharmacokinetic (PK) evidence to guide individualized dose selection. Valproic acid (VPA) is an effective treatment option for bipolar disorder in older adults, yet dosing largely ...
Yoo Jin Jang +2 more
wiley +1 more source
Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access
Clinical Pharmacology &Therapeutics, EarlyView.Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian +5 more
wiley +1 more source
Anti-oxidant, anti-apoptotic, and protective effects of myricitrin and its solid lipid nanoparticle on streptozotocin-nicotinamide induced diabetic nephropathy in type 2 diabetic male mice [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Reza Mohebbati
doaj +1 more source
Cystatin C and renal function in pediatric kidney transplant recipients
Brazilian Journal of Medical and Biological Research, 2009 In clinical practice, the glomerular filtration rate (GFR) is often determined with serum creatinine. However, studies have shown cystatin C to be a better parameter for the diagnosis of impaired renal function.
M.C.P. Franco +5 more
doaj +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Abemaciclib increases serum creatinine by inhibiting renal tubular transporters rather than reducing true glomerular filtration rate, a phenomenon known as pseudo‐acute kidney injury. Creatinine–cystatin C discrepancy and genetic determinants of this elevation remain insufficiently characterized in Japanese patients.
Hiroaki Watanabe +5 more
wiley +1 more source
Absolute differences between measured and estimated 1-year GFR changes vs baseline measured GFR.
, 2012 The absolute differences between 1-year GFR changes for both CKD-Epi (Upper panel) and aMDRD (Lower panel) formulas significantly increase for increasing values of GFR. Continuous lines are regression lines.
Piero Ruggenenti (180711) +16 more
core +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Anakinra, an interleukin‐1 receptor antagonist, shows promise for reducing inflammatory complications of premature birth. However, the pharmacokinetics (PK) of anakinra in neonates has not been characterized, limiting evidence‐based dosing. This study aimed to develop a population PK model for anakinra to guide dosing in preterm neonates.
Jia Li +27 more
wiley +1 more source