Results 91 to 100 of about 338,732 (239)
Автоматика и телемеханика, 2022 Рассматривается ресурсная гетерогенная система массового обслуживания с гибкой системой реагирования на запросы, состоящая из двух узлов. Каждый узел обладает некоторой емкостью ресурса для обслуживания (буферного пространства) и, следовательно, потенциальной возможностью отклика на поступившее требование, которое формирует запрос на предоставление ...
openaire +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Involvement of digestive system in COVID-19: manifestations, pathology, management and challenges
Therapeutic Advances in Gastroenterology, 2020 The pandemic of novel coronavirus disease (COVID-19) has developed as a tremendous threat to global health. Although most COVID-19 patients present with respiratory symptoms, some present with gastrointestinal (GI) symptoms like diarrhoea, loss of ...
Song Su +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Frontiers in EndocrinologyContextThe condition when a person’s gender identity does not match the sex assigned at birth is called gender incongruence (GI). Numbers of GI people seeking medical care increased tremendously over the last decade.
Claudia Boettcher +13 more
doaj +1 more source
Infinite-Dimensional Lie Algebras of Generalized Block Type [PDF]
, 1999 This paper investigates a class of infinite-dimensional Lie algebras over a field of characteristic 0 which are called here Lie algebras of generalized Block type, and which generalize a class of Lie algebras originally defined by Richard Block.
Osborn, J. Marshall, Zhao, Kaiming
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Gastrointestinal Fellowship Education in Korea
The Korean Journal of Gastroenterology, 2019 Since the residency training program in internal medicine changed from a four-year to a three-year program in 2017 in Korea, issues of an optimal training program for the gastrointestinal (GI) fellowship has arisen. Currently, the evaluation criteria for
Soon Man Yoon, Jae Myung Cha
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source