Results 91 to 100 of about 272,142 (259)

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

FEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui, Ariel Kushmaro, Hana Barak, Anja Poehlein, Rolf Daniel, Hans‐Jürgen Mägert   +5 more
wiley   +1 more source

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

FEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski, Irene Cortijo, Shruti Bhargava, Bernard Jover, Fabrice Raynaud, Juliana H Boukhaled, Anne‐Dominique Lajoix, Vera Jankowski, Joachim Jankowski, Magali Cordaillat‐Simmons, Àngel Argilés, Nathalie Gayrard, Flore Duranton, Jonas Laget   +13 more
wiley   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

The Long Term Effects of a 12‐Session Community Exercise Program on Health Measures in Cancer Patients

Aging and Cancer, EarlyView.
ABSTRACT Purpose To assess the long‐term effects of a community cancer exercise program on quality of life, fatigue, weight, waist circumference, physical activity levels, lower extremity strength, body mass index (BMI), heart rate, and blood pressure, across non‐metastatic and metastatic patients.
Isaac Oppong, Roozbeh Naemi
wiley   +1 more source

Risk analysis of the Unity 1.5T MR‐Linac adapt‐to‐shape workflow

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background and Purpose The adapt‐to‐shape (ATS) workflow on the Unity MR‐Linac (Elekta AB, Stockholm, Sweden) allows for full replanning including recontouring and reoptimization5. Additional complexity to this workflow is added when the adaptation involves the use of MIM Maestro (MIM Software, Cleveland, OH) software in conjunction with ...
Jiayi Liang, Eric Aliotta, Neelam Tyagi, Paola Godoy Scripes, Nicolas Côté, Ergys Subashi, Qijie Huang, Lian Sun, Ching‐Yun Chan, Angela Ng, Theresa Wunner, Victoria Brennan, Kaveh Zakeri, James Mechalakos   +13 more
wiley   +1 more source

Developing reference plans for evaluating global clinical trials credentialing and PSQA systems

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To develop a practical framework for creating a diverse set of validated reference plans (varying in complexity) and implement a workflow to introduce beam modeling, calibration, and delivery errors into the reference cohort to test and compare various dosimetry audit methodologies.
Fre'Etta M. D. Brooks, Mohammad Hussein, Jessica Lye, Christopher L. Nelson, Nakamura Mitsuhiro, Mallory C. Glenn, Patricia Diez, Rushil Patel, Maddison Shaw, Ileana Silvestre Patallo, Miriam Barry, Catharine H. Clark, Joerg Lehmann, Stephen F. Kry   +13 more
wiley   +1 more source

Effects of a novel weight-loss combination product containing orlistat and resveratrol on obesity: A multicenter randomized controlled study (EC-FIT)

Endocrine and Metabolic Science
Background: Orlistat, a weight loss medication, is often less effective due to poor adherence to the dietary and exercise recommendations. However, its effectiveness is often compromised by poor adherence to recommended lifestyle changes and side effects
Khin Maung Win, Tint Swe Latt, Aung Hlaing Bwa, Khin Maung Aye, Kyaw Soe Tun, Hardik Gandhi   +5 more
doaj  

GI Biopsy Crash Course

MedEdPORTAL, 2014
Introduction We recognized a need at our institution for a resource to facilitate self-learning of basic gastrointestinal (GI) histology and pathology.
Jeremy Parfitt, David Driman
doaj   +1 more source

Producing high quality cranial SRS plans with 4Pi planning technique in a commercial clinical solution

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To generate high‐quality stereotactic radiosurgery (SRS) plans for single cranial lesions using 4Pi planning technique and compare these to our clinical “status quo” plans. Methods Eighteen vestibular schwannoma (VS) patients previously planned with Varian Eclipse RapidArc and treated on a Varian TrueBeam using 6FFF MV photon beams ...
Ganesh Narayanasamy, Nishan Shrestha, Milan Bimali, Fen Xia, Zhong Su   +4 more
wiley   +1 more source

UR‐cycleGAN: Denoising full‐body low‐dose PET images using cycle‐consistent Generative Adversarial Networks

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose This study aims to develop a CycleGAN based denoising model to enhance the quality of low‐dose PET (LDPET) images, making them as close as possible to standard‐dose PET (SDPET) images. Methods Using a Philips Vereos PET/CT system, whole‐body PET images of fluorine‐18 fluorodeoxyglucose (18F‐FDG) were acquired from 37 patients to ...
Yang Liu, ZhiWu Sun, HaoJia Liu
wiley   +1 more source