Development and Evaluation of a Duplex Lateral Flow Assay for the Detection and Differentiation between Rabbit Haemorrhagic Disease Virus Lagovirus europaeus/GI.1 and /GI.2. [PDF]
Biology (Basel), 2022 Rabbit Haemorrhagic Disease Virus 2 (RHDV2, recently named Lagovirus europaeus/GI.2) was first reported in France in 2010 and has spread globally since then, replacing most of the circulating former RHDV (genotype GI.1) in many countries.
Fresco-Taboada A +8 more
europepmc +3 more sources
Indicators of the epizootic process manifestation of rabbit hemoragic disease (RHDV (GI.1) and RHDV2 (GI.2)) in Ukraine in 2021-2022 [PDF]
Bulletin "Veterinary biotechnology", 2023 agent of the disease was RHDV (GI.1), the incidence in rabbits was 50,9%, mortality was 43,3%, and lethality was 85,3%. In 6 farms where the causative agent of the disease was RHDV2 (GI.2), the incidence was 35,9%, mortality was 21,8%, and lethality was ...
Rhdv або +3 more
semanticscholar +2 more sources
MicroRNAs Regulate the Expression of Genes Related to the Innate Immune and Inflammatory Response in Rabbits Infected with Lagovirus europaeus GI.1 and GI.2 Genotypes. [PDF]
Int J Mol SciMicroRNAs (miR) are a group of small, non-coding RNAs of 17–25 nucleotides that regulate gene expression at the post-transcriptional level. Dysregulation of miRNA expression or function may contribute to abnormal gene expression and signaling pathways ...
Ostrycharz-Jasek E +4 more
europepmc +3 more sources
Transboundary and Emerging Diseases, 2021 Viruses that affect lagomorphs have decades of reported history of spillover events. One of these viruses is the causative agent of the so-called rabbit or 'lagomorph' haemorrhagic disease (e.g. Lagovirus europaeus/GI.1 and L. europaeus/GI.2). In particular, L. europaeus/GI.2 has shown a great capacity to recombine with existing lagoviruses.
Roser Velarde +8 more
openaire +5 more sources
Insulin inhibits the phosphorylation of α-Gi-2 in intact hepatocytes [PDF]
Biochemical Journal, 1995 Challenge of intact hepatocytes with insulin reduced the level of phosphorylated alpha-Gi-2 found under basal (resting) conditions. At maximally effective concentrations of insulin the steady-state labelling of alpha-Gi-2 was reduced by approximately 21%.
Morris NJ, Young P, Houslay MD
openaire +4 more sources
Transboundary and Emerging Diseases, 2021 Rabbit haemorrhagic disease (RHD) is a major threat to domestic and wild European rabbits. Presently, in Europe, the disease is caused mainly by Rabbit haemorrhagic disease virus 2 (RHDV2/b or Lagovirus europaeus GI.2), the origin of which is still unclear, as no RHDV2 reservoir hosts were identified.
Andreia Pinto +11 more
openaire +6 more sources
Worldwide rapid spread of the novel rabbit haemorrhagic disease virus (GI.2/RHDV2/b)
Transboundary and Emerging Diseases, 2019 We describe the extremely rapid worldwide spread of the Lagovirus europaeus/GI.2/RHDV2/b (henceforth GI.2), the causative infectious agent of the so-called 'novel' rabbit haemorrhagic disease of the European rabbit (Oryctolagus cuniculus). We tracked down all novel confirmed detections of GI.2 between May 2010 and November 2018 by carrying out a two ...
Carlos Rouco +4 more
openaire +5 more sources
Detection of a new emerging rabbit hemorrhagic disease type 2 virus (GI.2) in China [PDF]
, 2021 In May 2020, the first outbreak of rabbit viral hemorrhagic disease (RHD) caused by rabbit hemorrhagic disease virus type 2 (GI.2) occurred in Sichuan, China. The acute onset and short disease course resulted in rabbit mortalities as high as 42.86%.
Wanting Chen +8 more
openaire +3 more sources
Epidemiology of RHDV2 (Lagovirus europaeus/GI.2) in free-living wild European rabbits in Portugal
Transboundary and Emerging Diseases, 2017 As the detection of the first outbreak of a novel aetiological agent of rabbit haemorrhagic disease commonly called RHDV2 or RHDVb (Lagovirus europaeus/GI.2, henceforth GI.2) in France in 2010, the virus rapidly spread throughout continental Europe and nearby islands such as Great Britain, Sardinia, Sicily, the Azores and the Canary Islands among ...
Nuno Santos +12 more
openaire +6 more sources
High Mortality of Wild European Rabbits during a Natural Outbreak of Rabbit Haemorrhagic Disease GI.2 Revealed by a Capture-Mark-Recapture Study. [PDF]
Transbound Emerg Dis, 2023 Rabbit haemorrhagic disease virus (RHDV) GI.2 has caused significant declines in the abundance of wild European rabbits (Oryctolagus cuniculus), contributing to the species being recently classified as “endangered” in its native range.
Jiménez-Ruiz S +6 more
europepmc +2 more sources