Results 21 to 30 of about 5,839,150 (260)

Metastase Giant Cell Tumour of Bone ke Paru

Jurnal Kesehatan Andalas, 2020
Giant-cell tumor of bone (GCT) merupakan tumor tulang primer yang biasa terjadi pada dewasa muda usia 20-40 tahun. Giant-cell tumor of bone bersifat jinak tapi sangat destruktif lokal dan memiliki rekurensi yang sangat tinggi.
Dutia Gestin, Aswiyanti Asri, Hera Novianti   +2 more
doaj   +1 more source

Successful total en bloc spondylectomy of the L3 vertebra with a paravertebral giant cell tumor following preoperative treatment with denosumab: a case report

Journal of Medical Case Reports, 2019
Background Giant cell tumor is known to be a benign neoplasm that arises most commonly in the long bones, while cases in the spine are rare. Recently, denosumab, a monoclonal antibody that inhibits receptor activator of nuclear factor-kappa β ligand, has
Hideyuki Kinoshita, Sumihisa Orita, Tsukasa Yonemoto, Takeshi Ishii, Shintaro Iwata, Hiroto Kamoda, Toshinori Tsukanishi, Kazuhide Inage, Koki Abe, Masahiro Inoue, Masaki Norimoto, Tomotaka Umimura, Kazuki Fujimoto, Yasuhiro Shiga, Hirohito Kanamoto, Takeo Furuya, Kazuhisa Takahashi, Seiji Ohtori   +17 more
doaj   +1 more source

GIANT CELL-RICH OSTEOSARCOMA : A CASE REPORT [PDF]

, 1996
1996-12-27This report discusses a rare case of giant cell-rich osteosarcoma. The patient, a 19-year-old male, was diagnosed with a metadiaphyseal osteolytic lesion when he consulted a local doctor complaining of motion pain without swelling.
NAGASAKA, TETSURO, NAKASHIMA, NOBUO, SATO, KEIJI, YAMAMURA, SHIGEKI, IWATA, HISASHI, SUGIURA, HIDESHI   +5 more
core   +1 more source

Giant cell formation produced by laser microbeam irradiation of chromatin in Chinese hamster cells [PDF]

, 1981
A pulsed laser microbeam of wavelength 532 nm was used to produce visible small lesions in the nucleoplasm or in the cytoplasm of V79 Chinese hamster cells.
Cremer, Thomas, Turner, Anne, Liaw, Lih-Huei, Berns, Michael W., Berns, Michael W   +4 more
core   +1 more source

Localized tenosynovial giant cell tumor in the posterior compartment of the knee - A rare case report

Journal of Orthopaedic Reports, 2023
Background and purpose: Localized tenosynovial giant cell tumors represent a rare benign proliferative disorder of the synovial and surrounding tissue. This condition has insidious and unspecific symptoms that make its diagnosis challenging.
Luís Alves, Maria João Leite, Sara Lima, Tiago Torres, Manuel Gutierres   +4 more
doaj   +1 more source

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

Hepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam, Jianqing Yu, Hao Huang, Xiaofan Ding, Alissa M. Wong, Howard H. Leung, Anthony W. Chan, Kelvin K. Ng, Mingjing Xu, Xin Wang, Nathalie Wong   +10 more
wiley   +1 more source

An intraosseous giant cell granuloma: An uncommon presentation

Journal of Pharmacy and Bioallied Sciences, 2021
The giant cell granuloma is an identical reactive lesion which is mostly progressive in nature. The clinical behavior of these lesions varies from indolent to aggressive variant.
V Ravi Pavan, Vijayanirmala Subramani, S Senthoor Pandian, G V V Giri   +3 more
doaj   +1 more source

Giant Cell Tumor of the Tendon Sheath Causing Tarsal Tunnel Syndrome : A Case Report

, 2012
Tarsal tunnel syndrome is defined as a compressive neuropathy of posterior tibial nerve and its branches, medial and lateral plantar nerves , within the tarsal tunnel, which is located in the limited space behind medial malleolus. Giant cell tumor of the
WANG, CHENG-WEI;CHEN, CHIH-YU;WU, KARL;YANG, RONG-SEN, 王政為;陳致宇;吳凱文;楊榮森   +1 more
core   +1 more source

Immunohistochemical analyses of beta-catenin and cyclin D1 expression in giant cell tumor of bone (GCTB): A possible role of Wnt pathway in GCTB tumorigenesis. [PDF]

, 2009
Giant cell tumor of bone (GCTB) is a benign neoplasm but occasionally shows local recurrence, and histologically consists of osteoclast-like giant cells (GC) and stromal mononuclear cells (SC), which are capable of proliferation and osteoblastic ...
Nakashima, Masahiro, Kumagai, Kenji, Matsubayashi, Shohei, Naruke, Yuki, Egashira, Masayuki, Hayashi, Tomayoshi, Kondo, Hisayoshi, Shindo, Hiroyuki   +7 more
core   +1 more source

Exploring functional mechanisms underlying tumor initiation, EMT and cell migration [PDF]

, 2012
Cancer is one of the leading causes of death. A primary tumor forms when cells start to proliferate in an uncontrolled way and stop reacting to restraining signals.
Gruber, Dorothea Cornelia
core   +1 more source