Results 71 to 80 of about 5,839,150 (260)
Fibroma and giant-cell tumor of tendon sheath: a case report
Kátia Tôrres Batista,1 Heveline Becker de Moura,1 Maria Isabel Lima,2 Kikue Terada Abe3 1Department of Plastic Surgery and Pathology, 2Electron Microscopy Laboratory, 3Cytogenetic Laboratory, Sarah Hospital Brasilia, Brazil Abstract: A 53 ...
de Moura HB, Lima MI, Abe KT, Batista KT
core
This study provides the first evidence of natural TP53 variation between tree shrew subspecies and identifies somatic TP53 mutations in spontaneous tree shrew sarcomas. The high structural and functional conservation of tree shrew p53 with humans supports its utility as a relevant model for TP53‐related cancer research.
Yingying Cao +4 more
wiley +1 more source
Giant cell tumors of the bone are approximately 5% of all bone neoplasms. They place around the epiphysis of long bones in 75-90% of patients following after skeletal maturity. Only 0.5-0.6% of the giant cell tumor are located in the rib.
Atila Türkyılmaz +3 more
doaj
Introduction. Giant cell tumor of the bone is a rare benign lesion that infrequently affects the ribs, and if present, is usually located posteriorly. The rarity of this tumor poses diagnostic and therapeutic problems for physicians, especially when it ...
Amit Sharma, Amy E. Armstrong
doaj +1 more source
Pulmonary pleomorphic carcinoma (PPC) is a poorly differentiated non-small cell lung carcinoma, including squamous cell carcinoma, adenocarcinoma, or undifferentiated non-small cell lung carcinoma with at least 10% spindle and/or giant cells.
Jae-Han Jeong +3 more
doaj +1 more source
Human Monocytic Models Reveal Genotype‐Dependent Inflammatory Programs in VEXAS Syndrome
Objective VEXAS syndrome is a severe X‐linked autoinflammatory disorder caused by somatic mutations in ubiquitin‐like modifier activating enzyme 1 (UBA1), with clinical outcomes that vary by UBA1 genotype. We aimed to elucidate genotype‐specific inflammatory programs and identify potential therapeutic targets.
Kana Higashitani +10 more
wiley +1 more source
Giant cell tumor of soft tissue in groin region, clinically diagnosed as inguinal lymphadenopathy
Giant cell tumor of soft tissue is a rare primary soft tissue neoplasm with clinical and histological similarities to giant cell tumor of bone. Most cases arise from superficial soft tissue of extremities and present as painless and well circumscribed ...
Ahmad Sobhan Ardakani +1 more
doaj
Giant cell tumor of the capitate: an unusual case with 10 years follow-up
Giant cell tumor of the small bones, particularly the carpal bones of the hand, is exceedingly rare. We present a case report of giant cell tumor of the capitate in a 24 year-old female with 10 years postoperative follow-up.
Duman Serda +4 more
doaj +1 more source
Can p63 serve as a biomarker for giant cell tumor of bone? A Moroccan experience
Background Multinucleated giant cell-containing tumors and pseudotumors of bone represent a heterogeneous group of benign and malignant lesions. Differential diagnosis can be challenging, particularly in instances of limited sampling. The purpose of this
Hammas Nawal +6 more
doaj +1 more source

