Results 51 to 60 of about 5,839,150 (260)

Role of cancer stem cells in the development of giant cell tumor of bone

Cancer Cell International, 2020
The primary bone tumor is usually observed in adolescence age group which has been shown to be part of nearly 20% of the sarcomas known today. Giant cell tumor of bone (GCTB) can be benign as well as malignant tumor which exhibits localized dynamism and ...
Abdul Rouf War, Kai Dang, Shanfen Jiang, Zhongwei Xiao, Zhiping Miao, Tuanmin Yang, Yu Li, Airong Qian   +7 more
doaj   +1 more source

Black Hole Quencher‐Enhanced Plasmonic Photothermal Conversion

Advanced Science, EarlyView.
Researchers have developed a universal method to boost plasmonic photothermal conversion by attaching black hole quencher (BHQ) molecules to matched metal nanostructures. This hybrid approach increases efficiency by roughly threefold, reaching up to 69.1% in the near‐infrared‐II window.
Ruiyuan Zhang, Xinru Chen, Lin Shen, Jin Li   +3 more
wiley   +1 more source

AHNAK and inflammatory markers predict poor survival in laryngeal carcinoma. [PDF]

, 2012
AHNAK/Desmoyokin is a giant protein which has been recently linked to reorganization of the actin cytoskeleton, cellular migration and invasion. Here, we investigated the role of AHNAK in the pathophysiology of larynx carcinoma-one of the major subtypes ...
Reinhard Zeidler, Zeidler, Reinhard, Brandau, Sven, Sven Br, Bankfalvi, Agnes, Claudia A Dumitru, Dumitru, Claudia A., Lang, Stephan, Stephan Lang, Claudia A. Dumitru, Agnes Bankfalvi, Xiang Gu, Gu, Xiang, Sven Brandau   +13 more
core   +2 more sources

Nanometer Layer Coating to Lactose Particles for Optimization of Dexamethasone Pulmonary Delivery

Advanced Science, EarlyView.
Nanometer layer coating (NLC) was investigated and its mechanism illustrated by advanced characterization techniques. The effects and application for the inhalation of dexamethasone (DEX) were demonstrated through in vitro and in vivo evaluation. This approach increased DEX bioavailability and enabled the dose to be reduced to 1/30 of the intravenous ...
Qin Nie, Jiahe Liu, Xiangyu Zhao, Siying Yang, Han Sun, Bingqian Jia, Xiaohong Ren, Xintao Chen, Lixin Sun, Li Wu, Caifen Wang, Jiwen Zhang   +11 more
wiley   +1 more source

Localized type tenosynovial giant cell tumor with metastases to lungs and pleura: a case report and literature review

Journal of Medical Case Reports
Background Tenosynovial giant cell tumor is a rare soft tissue tumor of the synovium of joint, bursae, or tendon sheath. It is divided into localized or diffuse types on the basis of the growth pattern.
Afshan Ali Shaik, Manoj Kumar Panigrahi, Mahismita Patro, Vangapandu Sushmita, Pritinanda Mishra   +4 more
doaj   +1 more source

Palatal Swelling: A Diagnostic Enigma

Case Reports in Dentistry, 2016
Giant cell tumor (GCT) of bone is a giant-cell-rich bony lesion associated with abundant multinucleated osteoclast-type giant cells. It is a primary neoplasm of bone with characteristic clinical, radiological, and pathological features.
Ramalingam Suganya, Narasimhan Malathi, Harikrishnan Thamizhchelvan, Subramaniam Ramkumar, G. V. V. Giri   +4 more
doaj   +1 more source

Magneto‐NIR‐II‐Programmed Cascade Nanozymes Unlocking Blood–Brain Barrier Translocation and Autophagic Resistance in Glioblastoma

Advanced Science, EarlyView.
Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu, Yundi Wu, Shuai Zhang, Hongjuan Zhao, Jiping Zheng, Shiyang Shao, Jianqiang Chen, Xilong Wu   +7 more
wiley   +1 more source

A C‐Nucleoside Analogue of Cordycepin With High Metabolic Stability and Potent Anti‐Psoriatic Activity via Microneedle Delivery

Advanced Science, EarlyView.
This work identified CPD3a as a potent, stable C‐nucleoside cordycepin derivative. When formulated into microneedle array for topical treatment, it ameliorated psoriasis by rebalancing immunity and enhancing antioxidant defenses. ABSTRACT Psoriasis is a chronic inflammatory disorder characterized by immune dysregulation and epidermal hyperplasia ...
Wenfang Pan, Xinyue Shao, Yuanchen Zhong, Xujie Sun, Lixuan Yin, Zongyan He, Tianqun Lang, Yuanchao Xie   +7 more
wiley   +1 more source

WTAP Transcriptional Suppression by KLF9 Drives Osteoclastogenesis via M6A‐Mediated Regulation of CSF1R Signaling in Estrogen‐Deficient Osteoporosis

Advanced Science, EarlyView.
Scheme of the KLF9/WTAP/YTHDF2/m6A/CSF1R regulatory axis in osteoclastogenesis and estrogen‐deficient osteoporosis. WTAP‐mediated m6A modification of Csf1r mRNA governs osteoclastogenesis via a YTHDF2‐mediated pathway. Pathological upregulation of KLF9 drives Wtap transcription, leading to increased m6A deposition on the 3’‐UTR of Csf1r mRNA.
Chen Shen, Xin Liu, Gaoran Ge, Li Xu, Ziyu Zhang, Chang Lv, Hao Xu, Wenhao Li, Yi Qin, Qifeng Sheng, Qihan Wang, Hongxia Li, Jun Zhou, Huilin Yang, Dechun Geng   +14 more
wiley   +1 more source

Effect of bisphosphonates on bone giant cell tumor recurrence: a meta-analysis

Beni-Suef University Journal of Basic and Applied Sciences, 2022
Background We examined the impact of bisphosphonates as adjuvant therapy on the recurrence of giant cell bone tumors and the impact of various tumor stages and surgical techniques on this effect.
Marwa Mohsen, Hasnaa Osama, Mina Nicola, Haitham Saeed, Mohamed E. A. Abdelrahim   +4 more
doaj   +1 more source