Results 211 to 220 of about 26,677 (229)
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Current Oncology Reports, 2002
Giant cell tumor of bone is an enigmatic osseous neoplasm that is histologically benign but clinically shows local aggression and metastatic potential. The absence of clinical, radiographic, or pathologic features that are predictive of tumor behavior and patient outcome has resulted in recent attention to the pathobiology of giant cell tumor of bone ...
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Giant cell tumor of bone is an enigmatic osseous neoplasm that is histologically benign but clinically shows local aggression and metastatic potential. The absence of clinical, radiographic, or pathologic features that are predictive of tumor behavior and patient outcome has resulted in recent attention to the pathobiology of giant cell tumor of bone ...
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Giant Cell Tumors of the Sphenoid Bone
Neurosurgery, 1992Giant cell tumors of the sphenoid are rare; there are 36 previously reported cases. We report two cases of these tumors in women in their thirties, both associated with pregnancy. In the first patient, the tumor was removed via a transnasal transsphenoidal approach. In the second patient, a Le Fort maxillotomy was required.
David Uttley +4 more
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Giant Cell–Containing Tumors of Bone
Surgical Pathology Clinics, 2017Giant cell-containing tumors of bone are characterized morphologically by the presence of numerous osteoclastic giant cells. Correlation of clinical, radiologic, and laboratory findings is required for accurate histopathologic diagnosis and treatment of a giant cell-containing tumor of bone.
Zsolt Orosz, Nicholas A. Athanasou
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Surgical Pathology Clinics, 2012
This article provides an overview of giant cell tumor, including the typical clinical, radiographic, and pathologic findings, as well as some unusual features, such as multifocality and metastases. The article addresses recent advances in the molecular biology of giant cell tumor, particularly receptor activator of nuclear factor kappa B (RANK)-ligand ...
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This article provides an overview of giant cell tumor, including the typical clinical, radiographic, and pathologic findings, as well as some unusual features, such as multifocality and metastases. The article addresses recent advances in the molecular biology of giant cell tumor, particularly receptor activator of nuclear factor kappa B (RANK)-ligand ...
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Acta medica portuguesa, 1998
Giant-cell bone tumors are a rare entity. Only 7.5 to 15% are malignant tumors and correspond to 0.5% of all primary malignant bone tumors. This case report has an unusual localization (ischium) for this kind of tumor (+/- 0.6%). The patient was treated with radiotherapy alone, because local extension of the disease would require very aggressive ...
T Fernandes +3 more
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Giant-cell bone tumors are a rare entity. Only 7.5 to 15% are malignant tumors and correspond to 0.5% of all primary malignant bone tumors. This case report has an unusual localization (ischium) for this kind of tumor (+/- 0.6%). The patient was treated with radiotherapy alone, because local extension of the disease would require very aggressive ...
T Fernandes +3 more
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Giant-cell tumors of the bones of the hand
The Journal of Hand Surgery, 1980Twenty-eight giant-cell tumors of the bones of the hands of 21 patients were reviewed. There were 14 lesions in the phalanges, 12 in the metacarpals, and two in the carpal bones. Giant-cell tumor of bones develop at a younger age, have a shorter duration of symptoms, and recur more rapidly when they occur in the hand than when they occur in other ...
Robert M. Averill +2 more
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Giant cell tumors of the bones of the hand
The Journal of Hand Surgery, 1997The cases of all patients with a diagnosis of giant cell tumor of bone occurring in the hand and seen at the Mayo Clinic during a 50-year period were reviewed to assess the results of treatment. There were 5 lesions in the phalanges, 7 in the metacarpals, and 1 in the scaphoid.
Edward A. Athanasian +2 more
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Angiography in Giant-Cell Bone Tumors
Radiology, 1979Angiography was performed on 48 patients with giant-cell bone tumors. Sixty-four per cent were hypervascular; 25% were hypo- or moderately vascular; and 10% were avascular. Findings were similar in the 45 benign and 3 malignant tumors. There was no correlation between the findings and degree of histological aggressiveness.
Sidney Wallace +3 more
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The Study of Giant Cell Tumors in Bone
Orthopedics, 1989ABSTRACT: Twelve samples of giant cell tumor of bone were incubated in the authors' laboratory. The activity of the cells was documented by means of time lapse cinemicrography. The multinuclear giant cells (MGCs) with undegenerating nuclei migrating from the expiants had active ameboid movement and continuously changed their shapes.
Yu pu Lu, Quingyu Fan
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Medical Research Archives, 2016
Giant cell tumor of bone was originally described in the early 1800s. It is thought by most to be a benign tumor of bone, although “metastasis” to the lung is not uncommon. It is a tumor that consists of osteoclast like giant cells containing numerous nuclei as well as a mononuclear stromal component.
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Giant cell tumor of bone was originally described in the early 1800s. It is thought by most to be a benign tumor of bone, although “metastasis” to the lung is not uncommon. It is a tumor that consists of osteoclast like giant cells containing numerous nuclei as well as a mononuclear stromal component.
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