Results 21 to 30 of about 72,548 (342)

Giant cell tumor-like lesion of the urinary bladder: a report of two cases and literature review; giant cell tumor or undifferentiated carcinoma?

Diagnostic Pathology, 2009
Summary Giant cell tumor, excluding its prototype in bone, is usually a benign but local aggressive neoplasm originating from tendon sheath or soft tissue. Malignant behavior is uncommon.
Oznur Meltem, Huq Gülben, Aydın Övgü, Canberk Şule, Durak Haydar, Behzatoğlu Kemal, Özyalvaçlı Gül, Yıldız Pelin   +7 more
doaj   +1 more source

An intraosseous giant cell granuloma: An uncommon presentation

Journal of Pharmacy and Bioallied Sciences, 2021
The giant cell granuloma is an identical reactive lesion which is mostly progressive in nature. The clinical behavior of these lesions varies from indolent to aggressive variant.
V Ravi Pavan, Vijayanirmala Subramani, S Senthoor Pandian, G V V Giri   +3 more
doaj   +1 more source

Use of Denosumab in Children With Osteoclast Bone Dysplasias: Report of Three Cases. [PDF]

, 2019
Denosumab has been used successfully to treat disease-associated osteoclast overactivity, including giant cell tumor of bone. Given its mechanism of action, denosumab is a potent potential treatment of other osteoclast bone dysplasias including central ...
Bernthal, Nicholas M, Bukata, Susan, Eilber, Fritz C, Federman, Noah C, Felsenfeld, Alan L, Nelson, Scott D, Singh, Arun, Upfill-Brown, Alexander, Wesseling-Perry, Katherine   +8 more
core   +2 more sources

A Rationale for the Activity of Bone Target Therapy and Tyrosine Kinase Inhibitor Combination in Giant Cell Tumor of Bone and Desmoplastic Fibroma: Translational Evidences

Biomedicines, 2022
Giant cell tumor of bone (GCTB) and desmoplastic fibroma (DF) are bone sarcomas with intermediate malignant behavior and unpredictable prognosis. These locally aggressive neoplasms exhibit a predilection for the long bone or mandible of young adults ...
A. De Vita, S. Vanni, G. Miserocchi, V. Fausti, F. Pieri, C. Spadazzi, C. Cocchi, C. Liverani, C. Calabrese, R. Casadei, F. Recine, L. Gurrieri, Alberto Bongiovanni, T. Ibrahim, L. Mercatali   +14 more
semanticscholar   +1 more source

Primary hyperparathyroidism diagnosed after surgical ablation of a costal mass mistaken for giant-cell bone tumor: a case report

Journal of Medical Case Reports, 2011
Introduction Primary hyperparathyroidism is a common endocrine disorder characterized by elevated parathyroid hormone levels, which cause continuous osteoclastic bone resorption.
Vera Lara, Dolcino Mara, Mora Marco, Oddo Silvia, Gualco Marina, Minuto Francesco, Giusti Massimo   +6 more
doaj   +1 more source

A rare location for a common bone tumor, meta-diaphyseal giant cell tumor of bone in an adult patient

Rare Tumors, 2013
Primary bone tumors can be either benign or malignant considering their natural history and cellular morphology. Benign bone tumors are much more frequent than malignant ones although some of them like giant cell tumor of bone can behave just like a ...
Darioush M. Barzi, Sam H. Sámi, Ehsan Fallah   +2 more
doaj   +1 more source

Accuration of Fine Needle Aspiration Biopsy in Musculoskeletal Tumour [PDF]

, 2016
Fine needle aspiration biopsy (FNAB) has been reported to be the preferable choice of biopsy for musculoskeletal tumour. While FNAB appears to have advantages to core biopsy in the aspect of simplicity and cost, the diagnostic accuracy should be the most
Dewo, P. (Punto), Lanodiyu, Z. (Zikrina), Magetsari, R. (Rahadyan), Marseno, H. (Hengkie)   +3 more
core   +5 more sources

Giant cell tumor of bone: A single center study of 115 cases

Journal of Bone Oncology, 2022
Background: Giant cell tumor of bone (GCTB) is a locally aggressive bone tumor that represents about 4–5% of all primary bone tumors. It is characterized by aggressive growth, possible recurrence after surgical treatment and, in rare cases, metastasis ...
Niklas Deventer, Tymoteusz Budny, Georg Gosheger, Anna Rachbauer, Jan Puetzler, Jan Christoph Theil, Dmytrii Kovtun, Marieke de Vaal, Nils Deventer   +8 more
doaj   +1 more source

Palatal Swelling: A Diagnostic Enigma

Case Reports in Dentistry, 2016
Giant cell tumor (GCT) of bone is a giant-cell-rich bony lesion associated with abundant multinucleated osteoclast-type giant cells. It is a primary neoplasm of bone with characteristic clinical, radiological, and pathological features.
Ramalingam Suganya, Narasimhan Malathi, Harikrishnan Thamizhchelvan, Subramaniam Ramkumar, G. V. V. Giri   +4 more
doaj   +1 more source

Can p63 serve as a biomarker for giant cell tumor of bone? A Moroccan experience

Diagnostic Pathology, 2012
Background Multinucleated giant cell-containing tumors and pseudotumors of bone represent a heterogeneous group of benign and malignant lesions. Differential diagnosis can be challenging, particularly in instances of limited sampling. The purpose of this
Hammas Nawal, Laila Chbani, Youssef Alaoui Lamrani, Hind El, Harmouch Taoufiq, Siham Tizniti, Afaf Amarti   +6 more
doaj   +1 more source