Results 71 to 80 of about 21,214 (225)

Development and validation of a novel prognostic nomogram for patients with giant cell carcinoma of the lung: a population-based study [PDF]

open access: green, 2022
Feng Wang   +7 more
openalex   +1 more source

Targeted Degradation of eEF2K by a Structure‐Guided PROTAC Strategy for the Treatment of Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study developed an eEF2K‐targeting PROTAC, A6, that efficiently degrades eEF2K in TNBC cells, inhibiting tumor growth in vitro and in vivo. To enhance tumor‐specific delivery, we engineered A6@ZIF‐8, a pH‐sensitive nanocarrier, which improved drug accumulation at tumor sites, offering a promising therapeutic strategy for TNBC through targeted ...
Shijun Cao   +10 more
wiley   +1 more source

A case of squamous cell carcinoma arising from giant verruca vulgaris

open access: yesPifu-xingbing zhenliaoxue zazhi, 2022
A 54-years-old man presented with a plaque on his right knee for 10 years, with ulceration and scabs for 2 years. Dermatological examination revealed a demarcated, intact, keratinized plaque with tenderness, covered by thick scabs, on the right medial ...
Aili ZHANG   +4 more
doaj   +1 more source

Alterations of FHIT and P53 genes in keratocystic odontogenic tumor, dentigerous and radicular cyst [PDF]

open access: yes, 2008
BACKGROUND: The purpose of this study was to determine fragile histidine triad (FHIT) and p53 protein expression, and to analyze FHIT and p53 gene status in keratocystic odontogenic tumor (KOT), dentigerous cysts (DC) and radicular cysts (RC ...
Anić, Ivica   +6 more
core   +1 more source

Characterization of inflammatory pseudotumors in a large animal model of liver cancer

open access: yesAnimal Models and Experimental Medicine, EarlyView.
CT images in arterial and portal venous phases of liver lesions in Oncopig. Abstract Background The development of relevant and robust large animal models of hepatocellular carcinoma is needed to test new therapeutic strategies for this disease. Transgenic approaches hold promise in addressing this complex problem. One such model, the Oncopig, has been
Erik N. K. Cressman   +4 more
wiley   +1 more source

Loss of the PTCH1 tumor suppressor defines a new subset of plexiform fibromyxoma. [PDF]

open access: yes, 2019
BackgroundPlexiform fibromyxoma (PF) is a rare gastric tumor often confused with gastrointestinal stromal tumor. These so-called "benign" tumors often present with upper GI bleeding and gastric outlet obstruction.
Banerjee, Sudeep   +9 more
core   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

open access: yesBMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo   +9 more
wiley   +1 more source

Giant Solitary Nodular Trichoepithelioma: A Case Report and Review of Literature

open access: yesArchives of Clinical and Experimental Surgery, 2012
A giant solitary nodular trichoepithelioma (GST) is a rare trichogenic tumor, which may present as a pigmented lesion. A 45-year-old female was diagnosed as having a giant solitary nodular trichoepithelioma on her right forearm.
Sunder Goyal   +3 more
doaj   +1 more source

Basal cell skin cancer with metastasis to subcutaneous fat—a case report

open access: yesFrontiers in Surgery
Basal cell carcinoma (BCC) is a malignant neoplasm of the skin that originates from the cells of the basal layer of the epidermis and is the most common skin cancer worldwide, accounting for more than 75% of all nonmelanoma skin cancers.
Veronika Rumyantseva   +5 more
doaj   +1 more source

Solitary keratoacanthoma involving upper lip: a diagnostic dilemma - case report and a brief review [PDF]

open access: yes, 2010
Keratoacanthoma (KA) is a benign epithelial proliferative lesion which frequently occurs on the sun exposed areas of the skin. KA originates within the pilosebaceous apparatus of the skin and may be solitary or multiple.
Kamarthi, Nagaraju   +4 more
core   +1 more source

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