Results 51 to 60 of about 20,470 (212)

Cutaneous horns: are these lesions as innocent as they seem to be? [PDF]

, 2004
Background Cutaneous horns (cornu cutaneum) are uncommon lesions consisting of keratotic material resembling that of an animal horn. Cutaneous horn may arise from a wide range of the epidermal lesions, which may be benign, premalignant or malignant ...
Sivrioglu Nazan, Copcu Eray, Culhaci Nil
core   +2 more sources

Giant basal cell carcinoma (case report)

Russian Medical Inquiry, 2023
Basal cell skin cancer, or basal cell carcinoma (BCC), is the most common malignant tumor originating from skin keratinocytes or hair follicles. Giant BCCs are malignant skin neoplasms sized more than 5 cm with a greater tendency to invasion and metastasis than "standard" BCCs (sized less than 5 cm).
Yu.N. Grekova, N.V. Zilberberg, O.G. Rimar   +2 more
openaire   +1 more source

Clinical features, pathology, and surgical management of periocular giant basal cell carcinoma

Journal of Mind and Medical Sciences, 2020
Objectives. Basal cell carcinomas (BCCs) are malignant tumors which rarely metastasize, are slow-growing, and extensively locally destructive. BCCs more than 5 cm in diameter are defined as giant.
Oxana Madalina Grosu, Vladimir Poroch, Natalia Velenciuc, Sorinel Lunca   +3 more
doaj   +1 more source

Successful treatment of giant basal cell carcinoma with topical imiquimod 5% cream with long term follow-up

Indian Journal of Dermatology, 2014
The use of the topical Imiquimod 5% cream offers a noninvasive, nonsurgical, and an effective option for the treatment of primary small (5 cm) BCC with topical Imiquimod 5% cream are rare. We present our experience in the treatment of two giant tumors (6
M Chun-Guang, L Qi-Man, Z H Yu-Yun, C H Li-Hua, Tiffany Cheng, H Jian-De   +5 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

DNA aneuploidy as a topographic malignant transformation pattern in a pleomorphic adenoma of long-term evolution: a case report [PDF]

, 2011
Introduction We present a case of long-term evolution of a submandibular pleomorphic adenoma. There is little information about topographic malignant transformation patterns of pleomorphic adenomas.
Lorena Gallego, Luis Junquera, Josué Hernando, Manuel F Fresno, Ana Salas, Tommaso Cutilli   +5 more
core   +2 more sources

Liposomal delivery of hydrophobic RAMBAs provides good bioavailability and significant enhancement of retinoic acid signalling in neuroblastoma tumour cells [PDF]

, 2020
Retinoid treatment is employed during residual disease treatment in neuroblastoma, where the aim is to induce neural differentiation or death in tumour cells.
Bilip, Maja, Di Florio, Alessia, Eaton, Simon, Hart, Stephen L., Irving, Elsa, Maeshima, Ruhina, Mathiyalakan, Mayuran, Orford, Michael, Shah, Shreya, Simons, Claire, Stoker, Andrew W., Tagalakis, Aristides D.   +11 more
core   +4 more sources

Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: immunohistochemical and chromogenic in situ hybridization analysis [PDF]

, 2005
Introduction Metaplastic breast carcinomas constitute a heterogeneous group of neoplasms, accounting for less than 1% of all invasive mammary carcinomas.
Jorge S Reis-Filho, Fernanda Milanezi, Silvia Carvalho, Pete T Simpson, Dawn Steele, Kay Savage, Maryou BK Lambros, Emilio M Pereira, Jahn M Nesland, Sunil R Lakhani, Fernando C Schmitt, NE Hynes, Z Suo, Z Suo, Z Suo, Z Suo, DM Abd El-Rehim, MP DiGiovanna, R Bhargava, AL Harris, S Tsutsui, RA Walker, S Leibl, G Giaccone, J Baselga, W Pao, JG Paez, TJ Lynch, M Marty, J Baselga, KB Fallon, A Marquez, F Cappuzzo, T Takehana, C Corzo, K Al-Kuraya, JS Reis-Filho, ES Wargotz, ES Wargotz, ES Wargotz, ES Wargotz, ES Wargotz, AG Huvos, HA Oberman, JS Reis-Filho, J Isola, M Bilous, JW Lee, F Weber, TO Nielsen, D Santini, JS Reis-Filho, JS Reis-Filho, S Leibl, B Dunne, NK Popnikolov, A Sapino, PJ Barnes   +57 more
core   +2 more sources

Giant Cornu Cutaneum Superimposed on Basal Cell Carcinoma [PDF]

West Indian Medical Journal, 2015
Cornu cutaneum (CC) is a clinical term that describes the horn-like keratotic lesions extending vertically from the skin. Benign, premalignant or malignant lesions may be present at the base of CC. Seborrhoeic keratosis and squamous cell carcinoma (SCC) are the most commonly reported benign and malignant forms, respectively.
S, Agirgol, A T, Mansur, K, Bozkurt, H N, Azakli, A, Babacan, A, Dikmen   +5 more
openaire   +2 more sources

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source