Results 31 to 40 of about 6,122,672 (198)
The role of GLI2 in human basal cell carcinoma tumourigenesis [PDF]
, 2010 PhDAbnormal Sonic Hedgehog (SHH) signalling leads to increased transcriptional activation of its downstream effector, GLI2, which is implicated in the pathogenesis of a variety of human tumours, including human basal cell carcinoma (BCC).
Pantazi, Eleni
core +4 more sources
Slow‐growing pedunculated nodule
Clinical Case Reports, 2022 There have been limited reported cases of pedunculated basal cell carcinoma(BCC). Our case is original, and it combines two rare aspects of CBC: Pedunculated and giant. This uncommon aspect is rarely encountered.
Chaima Kouki +7 more
doaj +1 more source
Hepatology, EarlyView., 2022 Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel +93 more
wiley +1 more source
TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
Hepatology, EarlyView., 2022 The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam +10 more
wiley +1 more source
Explainable human‐in‐the‐loop healthcare image information quality assessment and selection
CAAI Transactions on Intelligence Technology, EarlyView., 2023 Abstract Smart healthcare applications cannot be separated from healthcare data analysis and the interactive interpretability between data and model. A human‐in‐the‐loop active learning approach is introduced to reduce the cost of healthcare data labelling by evaluating the information quality of unlabelled medical data and then screening the high ...
Yang Li, Sezai Ercisli
wiley +1 more source
Giant Basal Cell Carcinoma of the Lumbosacral Region: A Case Report and Literature Review [PDF]
Turkish Journal of Plastic Surgery, 2016 Objective: Although frequently regarded as a low grade malignancy, basal cell carcinoma (BCC) sometimes shows aggressive behavior. Giant BCC is defined as a lesion greater then 5 centimeter.
Arzu Akçal +4 more
doaj +1 more source
JPRAS Open, 2022 We herein report a 57-year-old man afflicted with multiple malignant tumors arising from a giant sebaceous nevus on his left parieto-temporal scalp and neck.
Masakatsu Hihara +4 more
doaj +1 more source
Surgical treatment of giant basal cell carcinoma of the face: our experience [PDF]
Liječnički vjesnik, 2022 Giant basal cell carcinoma (GBCC) is a rare skin tumor with the longest diameter greater than five cm.The main factors for its occurrence are considered to be the neglect of conventional basal cell carcinoma (BCC) by patients and the biological ...
Ivan Kovačić +3 more
doaj +1 more source
Giant-neglected facial Marjolin’s ulcer associated with perioperative blood loss anemia
Avicenna Journal of Medicine, 2020 Cutaneous squamous cell carcinoma (cSCC) is the second most common cancer in humans after basal cell carcinoma. Marjolin’s ulcer is a form of cutaneous malignancy, and mostly represents cSCC, arising from chronic burns and wounds.
Ahmad Kaako +2 more
doaj +1 more source
Rare Tumors, 2012 Giant cell arteritis is a granulomatous vasculitis of large and medium sized arteries manifesting as temporal arteritis and/or polymyalgia rheumatica.
Salem Alowami +3 more
doaj +1 more source