Challenges of denosumab in giant cell tumor of bone, and other giant cell-rich tumors of bone
Purpose of review Giant cell tumor of bone (GCTB) is an uncommon benign primary bone tumor, consisting of receptor activator of nuclear factor kappa-B (RANK) expressing reactive osteoclast-like giant cells and neoplastic spindle-shaped cells.
A. Lipplaa, S. Dijkstra, H. Gelderblom
semanticscholar +1 more source
On Making Magnetic-Flux-Rope $Ω$ Loops for Solar Bipolar Magnetic Regions of All Sizes by Convection Cells [PDF]
We propose that the flux-rope $\Omega$ loop that emerges to become any bipolar magnetic region (BMR) is made by a convection cell of the $\Omega$-loop's size from initially-horizontal magnetic field ingested through the cell's bottom. This idea is based on (1) observed characteristics of BMRs of all spans ($\sim$ 1000 km to $\sim$ 200,000 km), (2) a ...
arxiv +1 more source
O granuloma actínico de O'Brien é uma doença cutânea rara. Há muitas controvérsias na sua caracterização, podendo representar uma entidade nosológica distinta ou uma forma de granuloma anular em áreas expostas.
Rosana Lazzarini+3 more
doaj +1 more source
Prognostic factors for sarcomatoid carcinomas of lung: A single-centre experience
Background: Although lung sarcomatoid carcinomas (LSCa) arised from the epithelial tissue, they have very distinctive features than other non-small cell lung carcinomas in terms of histopathology and survival. It constitutes 0.1%–0.4% of all lung cancers.
Muhammet Sayan+6 more
doaj +1 more source
Clinical and ultrasonographic features in anterior ischemic optic neuropathy [PDF]
Background/Aim. Anterior ischemic optic neuropathy (AION) represent a segmental infarction of the optic nerve head which is supplied by the posterior ciliary arteries.
Jianu Dragos Cătălin+3 more
doaj +1 more source
Asymmetric Oxidation of Giant Vesicles triggers Curvature-associated Shape Transition and Permeabilization. Running title: Oxidation of Vesicles produces Curvature [PDF]
(200 words) Oxidation of unsaturated lipids is a fundamental process involved in cell bioenergetics as well as in cell death. Using giant unilamellar vesicles and a chlorin photosensitizer, we asymmetrically oxidized the outer or inner monolayers of lipid membranes.
arxiv +1 more source
Statistical Indicators of Collective Behavior and Functional Clusters in Gene Networks of Yeast [PDF]
We analyze gene expression time-series data of yeast S. cerevisiae measured along two full cell-cycles. We quantify these data by using q-exponentials, gene expression ranking and a temporal mean-variance analysis.
Tadic, Bosiljka+3 more
core +2 more sources
Atraumatic Ruptured Giant Renal Tumor
Massive hemoperitoneum due to spontaneous rupture of renal cell carcinoma is a rare presentation during emergency laparotomy. A 60-year-old female patient presented with severe abdominal pain, nausea, vomiting and abdominal distension.
Gezahen Negusse Ayane, Khutsafalo Kadimo
doaj
Peripheral giant cell granuloma of maxilla
It is often documented that chronic irritation could be an etiology of oral cancer; yet out of negligence little heed is paid to any sort of discomfort until it grows to a sizable mass where it is difficult to go unnoticed.
Nilima Sharma, Safia Rana, Sujata Jetley
doaj +1 more source
Are CD68 and Factor VIII-RA Expression Different in Central and Peripheral Giant Cell Granuloma of Jaw: An Immunohistochemical Comparative Study [PDF]
Objective: Central giant cell granuloma and peripheral giant cell granuloma of the jaw and oral cavity are identical in histopathologic features, although they are different in pathogenesis and clinical behavior.
Soudabeh SARGOLZAEİ+2 more
doaj +1 more source