Results 51 to 60 of about 26,644 (187)
Case Reports in Orthopedics, 2018 Case. Giant cell tumor of bone is a benign, aggressive neoplasm commonly arising in the femur, tibia, and distal radius and less commonly in the hands and feet.
Andrew Golz +3 more
doaj +1 more source
Dedifferentiated giant-cell tumor of bone with an undifferentiated round cell mesenchymal component
Rare Tumors, 2014 The dedifferentiated giant-cell tumor of the bone is a very rare variant of the giant-cell tumor (GCT). We report the clinical, radiographic and histological findings of a dedifferentiated GCT in which the dedifferentiated component consisted of small ...
Eréndira G. Estrada-Villaseñor +4 more
doaj +1 more source
Management of post‐implant fibrous dysplasia in the maxilla: A case study
Clinical Advances in Periodontics, EarlyView.Abstract Background Fibrous dysplasia is generally rare, and even rarer in older adults. Special care is needed when altering the alveolar bone in these cases, especially if an implant is involved. This case study highlights such a scenario. Methods This case study details the experience of a 63‐year‐old African American female who presented with a ...
Yousef Taha Y. Amrou +4 more
wiley +1 more source
Giant-cell tumor of bone: treatment options and role of denosumab
Biologics: Targets & Therapy, 2015 Arun S Singh,1 Neal S Chawla,2 Sant P Chawla2 1Sarcoma Service, Division of Hematology/Oncology, University of California, Los Angeles, 2Sarcoma Oncology Center, Santa Monica, CA, USA Abstract: Giant-cell tumor of bone is a rare, locally aggressive ...
Singh AS, Chawla NS, Chawla SP
doaj
Mitochondrial dysfunction: Related diseases, influencing factors, and detection
Interdisciplinary Medicine, EarlyView.Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li +9 more
wiley +1 more source
Giant cell tumor of soft tissue of hand: simple but rare diagnosis, which is often missed
Clinics and Practice, 2011 Giant cell tumor of soft tissue originally described in 1972 in two different series by Salm and Sissons is a rare entity, which is clinically and histopathologically indistinguishable from giant cell tumor of bone.
Sarwan Kumar, Lynn F. Carter
doaj +1 more source
Patient‐derived xenograft models in pan‐cancer: From bench to clinic
Interdisciplinary Medicine, EarlyView.Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li +5 more
wiley +1 more source
Primary mediastinal giant cell tumor
Rare Tumors, 2009 Giant cell tumor of soft tissue is a rare tumor first described by Salm and Sissons in 1972 as being a distinct entity.1 Histologically, it is composed of multinucleated giant cells dispersed among mononuclear cells, and is indistinguishable from its ...
Jela Bandovic +3 more
doaj +1 more source
Peri‐implant inflammation increases the risk of osteonecrosis in mice treated with bisphosphonate
Journal of Periodontology, EarlyView.Abstract Background Bisphosphonates (BPs) are effective in managing bone diseases due to their anti‐resorptive properties but are linked to medication‐related osteonecrosis of the jaw (MRONJ), particularly concerning dental implants. This study explored the combined impact of ligature‐induced peri‐implant inflammation and zoledronic acid (ZA), a BP ...
Ana Bujila +11 more
wiley +1 more source
Giant-cell tumor of the patella: An uncommon cause of fracture
Archives of Clinical and Experimental Surgery, 2017 Primary patellar tumors are highly unusual. Most are benign neoplasms with giant-cell tumors being the most common, followed by chondroblastomas and aneurysmal bone cysts.
Esther Carbó-Laso +6 more
doaj +1 more source