Results 41 to 50 of about 64,522 (303)

Denosumab versus zoledronic acid in cases of surgically unsalvageable giant cell tumor of bone: A randomized clinical trial

Journal of Bone Oncology, 2019
Background: Although denosumab has been approved as an antiresorptive agent for giant cell tumor of bone, its efficacy has not been proven. Objectives: To compare the efficacy and safety of denosumab and zoledronic acid treatment in patients with ...
Shenglong Li, Peng Chen, Qiankun Yang
doaj   +1 more source

Neoadjuvant and Adjuvant Treatment with Denosumab in Aggressive Giant-cell Tumor of Bone in the Proximal Fibula: a Case Report

Folia Medica, 2018
Giant cell tumor of bone is a histologically benign but locally aggressive osteolytic lesion, capable of spreading ‘benign’ metastases mainly to the lungs. Since its description as a separate entity, surgery has been the mainstay of treatment.
Marinova Violeta V., Slavchev Svetoslav A., Patrikov Kircho D., Tsenova Petya M., Georgiev Georgi P.   +4 more
doaj   +1 more source

Inpatient Food Insecurity and Pediatric Hematology Oncology Hospitalization Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Children with cancer and blood disorders are at risk for food insecurity (FI). We aimed to describe the association of inpatient food insecurity (IFI) and hospitalization outcomes among patients admitted to the pediatric hematology oncology service. Of 325 caregivers screened for IFI, 60 (18.6%) screened positive.
Joanna M. Robles, Greg Russell, Leila H. DeWitt, Kimberly Montez, Callie L. Brown   +4 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Tumor de Células Gigantes del Primer Metacarpiano [PDF]

, 1991
Se presenta un caso de tumor de células gigantes que afecta al primer metacarpiano. El tratamiento consistió en la resección en bloque del metacarpiano y su sustitución por injerto cortico-esponjoso de cresta ilíaca.A case of giant cell tumor affecting ...
Arríete Peris, J. C., Escalera Alonso, J., Más Piedra, P., Tecles Tomas, J. A.   +3 more
core  

Odontogenic Myxoma Of The Maxilla: A Clinical Case Report And Review Of Literature [PDF]

, 2013
Odontogenic myxomas are rare benign mesenchymal  tumours of head and neck with a potential for  local infiltration and recurrence. They appear to originate from the dental papilla, follicle or periodontal ligament in mandible and less commonly the ...
Bhardwaj, Vikram, Garg, Bhawna, Munjal, Manish, Sood, Neena   +3 more
core   +2 more sources

Giant Cell Tumor of the Sphenoid Bone [PDF]

Skull Base, 1998
Giant cell tumor of the sphenoid bone is extremely unusual. This tumor is usually located in long bones and is rarely located in the cranial vault. It must be differentiated from reparative granuloma and the Brown tumor of hyperparathyroidism. This case report is only the second involving a patient in the first decade.A 9-year-old girl presented with ...
K A, Kattner, A, Stroink, K, Gupta, T, Fukushima, C, Li   +4 more
openaire   +2 more sources

Malignização primária no tumor de células gigantes: um estudo de caso [PDF]

, 2009
CONTEXT: Primary malignancy in giant cell tumor (PMGCT) is rare. It is defined as a high-grade sarcoma originating in a giant cell tumor (GCT) and seems to behave less aggressively than its secondary counterpart does.
BAPTISTA, André Mathias, BISPO JÚNIOR, Rosalvo Zósimo, BRUNO, José Marcello, CAMARGO, Olavo Pires de, IDA, Cristiane Marie, OLIVEIRA, Cláudia Regina Gomes Cardim Mendes de, RIBEIRO, Marcelo Barbosa   +6 more
core   +1 more source

Challenges of denosumab in giant cell tumor of bone, and other giant cell-rich tumors of bone

Current Opinion in Oncology, 2019
Purpose of review Giant cell tumor of bone (GCTB) is an uncommon benign primary bone tumor, consisting of receptor activator of nuclear factor kappa-B (RANK) expressing reactive osteoclast-like giant cells and neoplastic spindle-shaped cells.
Lipplaa, A., Dijkstra, S., Gelderblom, H.   +2 more
openaire   +5 more sources

Toward Wireless Implantable Robotic Systems Driven by Magnetic Field for Personalized Therapy

Advanced Robotics Research, EarlyView.
Robotic materials are playing an increasingly vital role in enabling sensing and actuation at small scales. This perspective highlights recent advances in magnetic materials and magnetically actuated devices for wireless sensing, actuation, and energy harvesting toward implantable robotic systems for closed‐loop therapy.
Yusheng Wang, Ruijian Ge, Xiaoguang Dong
wiley   +1 more source