Results 21 to 30 of about 166,449,558 (233)

Role of cancer stem cells in the development of giant cell tumor of bone

Cancer Cell International, 2020
The primary bone tumor is usually observed in adolescence age group which has been shown to be part of nearly 20% of the sarcomas known today. Giant cell tumor of bone (GCTB) can be benign as well as malignant tumor which exhibits localized dynamism and ...
Abdul Rouf War, Kai Dang, Shanfen Jiang, Zhongwei Xiao, Zhiping Miao, Tuanmin Yang, Yu Li, Airong Qian   +7 more
doaj   +1 more source

Multicentric Giant Cell Tumor of Bone

, 2023
The typical presentation of giant cell tumor of bone is a solitary lesion involving the meta-epiphyseal region of the long bones. The presence of more than one distinct giant cell tumor in the same patient is rare.
Alvarado, Rebeca Angulo, Nitta, Yuji, Errani, Costantino, Tsukamoto, Shinji, Donati, Davide Maria, Righi, Alberto, Mavrogenis, Andreas F.   +6 more
core   +2 more sources

Giant cell tumor-like lesion of the urinary bladder: a report of two cases and literature review; giant cell tumor or undifferentiated carcinoma?

Diagnostic Pathology, 2009
Summary Giant cell tumor, excluding its prototype in bone, is usually a benign but local aggressive neoplasm originating from tendon sheath or soft tissue. Malignant behavior is uncommon.
Oznur Meltem, Huq Gülben, Aydın Övgü, Canberk Şule, Durak Haydar, Behzatoğlu Kemal, Özyalvaçlı Gül, Yıldız Pelin   +7 more
doaj   +1 more source

DISTAL TIBIAL RECONSTRUCTION WITH INTRAMEDULLARY NAIL COMBINED WITH T-PLATE FOLLOWING EN-BLOC-EXCISION OF GIANT CELL TUMOR OF DISTAL TIBIA: CASE-REPORT

Journal Orthopaedi and Traumatology Surabaya, 2021
Background: Giant cell tumor is locally aggressive benign tumor that occur more common in distal femur, proximal tibia, and distal radius, and has tendency for recurrence and has capability for metastatize.
Mujaddid Idulhaq, Fajar Baskoro Gardjito, Ibnu Yudistiro   +2 more
doaj   +1 more source

Giant cell tumor of bone arising in long bones possibly originates from the metaphyseal region [PDF]

, 2016
Giant cell tumor of bone (GCTB) is a primary benign bone tumor with a locally aggressive character. Definitive descriptions of the site of origin for this type of tumor are not available. The aim of the present study was to evaluate the site of origin of
Ishiguro, Naoki, Arai, Eisuke, Tsukushi, Satoshi, Nishida, Yoshihiro, Kozawa, Eiji, Urakawa, Hiroshi, Futamura, Naohisa   +6 more
core   +1 more source

Immunohistochemical analyses of beta-catenin and cyclin D1 expression in giant cell tumor of bone (GCTB): A possible role of Wnt pathway in GCTB tumorigenesis. [PDF]

, 2009
Giant cell tumor of bone (GCTB) is a benign neoplasm but occasionally shows local recurrence, and histologically consists of osteoclast-like giant cells (GC) and stromal mononuclear cells (SC), which are capable of proliferation and osteoblastic ...
Nakashima, Masahiro, Kumagai, Kenji, Matsubayashi, Shohei, Naruke, Yuki, Egashira, Masayuki, Hayashi, Tomayoshi, Kondo, Hisayoshi, Shindo, Hiroyuki   +7 more
core   +1 more source

Primary hyperparathyroidism diagnosed after surgical ablation of a costal mass mistaken for giant-cell bone tumor: a case report

Journal of Medical Case Reports, 2011
Introduction Primary hyperparathyroidism is a common endocrine disorder characterized by elevated parathyroid hormone levels, which cause continuous osteoclastic bone resorption.
Vera Lara, Dolcino Mara, Mora Marco, Oddo Silvia, Gualco Marina, Minuto Francesco, Giusti Massimo   +6 more
doaj   +1 more source

Giant cell tumor of bone: A single center study of 115 cases

Journal of Bone Oncology, 2022
Background: Giant cell tumor of bone (GCTB) is a locally aggressive bone tumor that represents about 4–5% of all primary bone tumors. It is characterized by aggressive growth, possible recurrence after surgical treatment and, in rare cases, metastasis ...
Niklas Deventer, Tymoteusz Budny, Georg Gosheger, Anna Rachbauer, Jan Puetzler, Jan Christoph Theil, Dmytrii Kovtun, Marieke de Vaal, Nils Deventer   +8 more
doaj   +1 more source

A rare location for a common bone tumor, meta-diaphyseal giant cell tumor of bone in an adult patient

Rare Tumors, 2013
Primary bone tumors can be either benign or malignant considering their natural history and cellular morphology. Benign bone tumors are much more frequent than malignant ones although some of them like giant cell tumor of bone can behave just like a ...
Darioush M. Barzi, Sam H. Sámi, Ehsan Fallah   +2 more
doaj   +1 more source

Emerging trends and focus of giant cell tumor of bone research from 2001–2021: A visualization research

Frontiers in Oncology, 2022
Giant cell tumor of bone is a highly invasive benign tumor with a high postoperative recurrence rate. Objective: This study aims to analyze the research hotspots and trends of global research on giant cell tumor of bone in the past 20 years, to provide a
Ying-Song Han, Yi-Fan Yang, Gang Chen, Hai-Liang Yu, Zhi-Guo Zhang, Bin Zhou   +5 more
doaj   +1 more source