Results 31 to 40 of about 152,261 (253)
Scientia Agricola, 2019 : Meloidogyne species are widely distributed in coffee growing areas in Brazil, where M. paranaensis is responsible to significant losses to the crop. One of the main management strategies is the use of resistant cultivars, such as Apoatã rootstock and ...
Luciana Harumi Shigueoka +6 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Nodal and cripto-1: distinct functions regulate trophoblast specification in mouse pregnancy
Frontiers in Cell and Developmental BiologyIntroductionProper placentation is essential for fetal growth and development in mammals. Nodal signaling is essential to ensure proper embryo development and requires Cripto-1 as a co-receptor.
Laura Girardet +5 more
doaj +1 more source
GIANT CELLS AND GIANT CELL LESIONS OF ORAL CAVITY- A REVIEW
Cumhuriyet Dental Journal, 2014 Giant cells are large mononucleated or multinucleated cells that are seen in a variety of physiological as well as pathological conditions. Multinucleated giant cells (MGCs) are important mediators of tissue remodeling and repair and also for removal of ...
Ashish Shrestha +3 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Frontiers in Plant ScienceRoot-knot nematodes are polyphagous parasitic nematodes that cause severe losses in the agriculture worldwide. They enter the root in the elongation zone and subtly migrate to the root meristem where they reach the vascular cylinder and establish a ...
Jose Domínguez-Figueroa +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Floret-like multinucleated giant cells in neurofibroma
Diagnostic Pathology, 2007 This short report discusses a case of neurofibroma containing floret-like multinucleated giant cells. This being the second such case in the literature.
Golka Dariusz, Shaktawat Sameer
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Fungal cell gigantism during mammalian infection. [PDF]
PLoS Pathogens, 2010 The interaction between fungal pathogens with the host frequently results in morphological changes, such as hyphae formation. The encapsulated pathogenic fungus Cryptococcus neoformans is not considered a dimorphic fungus, and is predominantly found in ...
Oscar Zaragoza +5 more
doaj +1 more source