Phage therapy: awakening a sleeping giant [PDF]
Emerging Topics in Life Sciences, 2017 For a century, bacterial viruses called bacteriophages have been exploited as natural antibacterial agents. However, their medicinal potential has not yet been exploited due to readily available and effective antibiotics.
D. Roach, L. Debarbieux
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A giant Pseudomonas phage from Poland [PDF]
Archives of Virology, 2013 A novel giant phage of the family Myoviridae is described. Pseudomonas phage PA5oct was isolated from a sewage sample from an irrigated field near Wroclaw, Poland. The virion morphology indicates that PA5oct differs from known giant phages. The phage has
Z. Drulis-Kawa +4 more
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A Novel Singleton Giant Phage Yong-XC31 Lytic to the Pyropia Pathogen Vibrio mediterranei [PDF]
Applied Sciences, 2021 Vibrio mediterranei 117-T6 is extensively pathogenic to several Pyropia species, leading to the death of conchocelis. In this study, the first V. mediterranei phage (named Vibrio phage Yong-XC31, abbreviated as Yong-XC31) was isolated.
Lihua Xu +8 more
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Global Proteomic Profiling of Salmonella Infection by a Giant Phage [PDF]
Journal of Virology, 2018 “Giant” phages with genomes >200 kb are being isolated in increasing numbers from a range of environments. With hosts such as Salmonella enterica, Pseudomonas aeruginosa, and Erwinia amylovora, these phages are of interest for phage therapy of multidrug ...
S. Weintraub +14 more
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Genetic Diversity Among Independent Isolates of the Dolichocephalovirinae Subfamily
BacteriaMembers of the Dolichocephalovirinae subfamily are giant viruses with an elongated head and a flexible tail that is used to infect Caulobacter strains.
Bert Ely, Quill Thomas, Tannaz Mohammadi
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Identification of Essential Genes in the Salmonella Phage SPN3US Reveals Novel Insights into Giant Phage Head Structure and Assembly [PDF]
Journal of Virology, 2016 Giant tailed bacterial viruses, or phages, such as Pseudomonas aeruginosa phage ϕKZ, have long genomes packaged into large, atypical virions. Many aspects of ϕKZ and related phage biology are poorly understood, mostly due to the fact that the functions ...
Julie A. Thomas +10 more
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Nested Protein Lattices in a Giant Phage Capsid Suggest Partial Maturation and a Residual Scaffold [PDF]
Microscopy and Microanalysis, 2020 “Giant” phages - also known as “jumbo” phages - have genomes in excess of >200 kbp dsDNA and correspondingly complex assembly pathways (Hendrix, 2009).
B. Heymann +7 more
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Transcription Profiling of
mBio, 2017 Bacteriophage AR9 is a recently sequenced jumbo phage that encodes two multisubunit RNA polymerases. Here we investigated the AR9 transcription strategy and the effect of AR9 infection on the transcription of its host, Bacillus subtilis.
Daria Lavysh +4 more
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The Potential of Co-Evolution and Interactions of Gut Bacteria–Phages in Bamboo-Eating Pandas: Insights from Dietary Preference-Based Metagenomic Analysis [PDF]
MicroorganismsBacteria and phages are two of the most abundant biological entities in the gut microbiome, and diet and host phylogeny are two of the most critical factors influencing the gut microbiome. A stable gut bacterial community plays a pivotal role in the host’
Mingyue Zhang +3 more
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Unexpected diversity and ecological significance of uncultivable large virus-like particles in aquatic environments. [PDF]
ISME CommunThe discovery of Jumbo phages and giant viruses of microeukaryotes has transformed our perception of the virosphere. Metagenomic and metatranscriptomic data further highlight their diversity and ecological impact.
Billard H +14 more
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