Results 41 to 50 of about 7,517 (145)

Bacteriophage-encoded virion-associated enzymes to overcome the carbohydrate barriers during the infection process [PDF]

, 2017
Bacteriophages are bacterial viruses that infect the host after successful receptor recognition and adsorption to the cell surface. The irreversible adherence followed by genome material ejection into host cell cytoplasm must be preceded by the passage ...
Briers, Yves, Drulis-Kawa, Zuzanna, Maciejewska, Barbara, Majkowska-Skrobek, Grazyna, Łątka, Agnieszka   +4 more
core   +1 more source

Diversity, transfer potential, and transcriptional activity of virus‐carried antibiotic resistance genes in global estuaries

iMetaOmics, EarlyView.
Estuaries are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been proposed as key reservoirs and important disseminators of ARGs in environments, their contribution to the estuarine antibiotic resistome remains largely unknown.
Xiao‑Qing Luo, Xiyang Dong, Jia‑Ling Li, Ji‐Cheng Yao, Ziqi Peng, Qi Li, Zi‐Wen Yang, Yang Yuan, Wen‑Jun Li, Pandeng Wang   +9 more
wiley   +1 more source

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

iNew Medicine, EarlyView.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng, Qianqian Wang, Jiachen Zhang, Sandra Chiu   +3 more
wiley   +1 more source

Biodegradability and tissue reaction of random copolymers of L-leucine, L-aspartic acid, and L-aspartic acid esters [PDF]

, 1977
A series of copoly(α-amino acids) with varying percentages of hydrophilic (l-aspartic acid) and hydrophobic monomers (l-leucine, ß-methyl-l-aspartate, and ß-benzyl-l-aspartate) were implanted subcutaneously in rats and the macroscopic degradation ...
Bantjes, A., Feijen, J., Marck, K.W., Sederel, W.L., Wildevuur, Ch.R.H.   +4 more
core   +3 more sources

Structures and mechanism of E2‐CBASS anti‐phage system

mLife, EarlyView.
Abstract Bacteria deploy diverse innate immune systems to combat bacteriophage infections. The cyclic‐oligonucleotide‐based anti‐phage signaling system (CBASS) is a type of innate prokaryotic immune system. CBASS synthesizes cyclic‐oligonucleotide through cGAS/DncV‐like nucleotidyltransferases (CD‐NTases) to activate downstream effectors, which kill ...
Jun Xiao, Yan Yan, Jing Li, Greater Kayode Oyejobi, Dongyang Lan, Bin Zhu, Zhiming Wang, Longfei Wang   +7 more
wiley   +1 more source

An in vivo study of the host response to starch-based polymers and composites subcutaneously implanted in rats [PDF]

, 2005
Implant failure is one of the major concerns in the biomaterials field. Several factors have been related to the fail but in general these biomaterials do not exhibit comparable physical, chemical or biological properties to natural tissues and ...
Al-Saffar, Al-Saffar, Alves, Anderson, Anderson, Anderson, Anderson, Arnaout, Artursson, Azevedo, Bastioli, Bastioli, Bergsma, Bostman, Bostman, Clarke, Desevaux, Desevaux, Espigares, Fisher, Gomes, Hagerty, Heuff, Hu, Hunt, Jackson, Jansen, Jasty, Kao, Kao, Kellar, Khouw, Khouw, Kidd, Kohane, Lickorish, Lo, Malafaya, Maloney, Marques, Marques, McLennan, Mendes, Ooms, Parker, Parker, Pieper, Poshusta, Ratner, Reis, Rhodes, Rosen, Santavirta, Santavirta, Smetana, Souillac, Sunderkotter, Sunderkotter, Tabata, Tang, Terada, van Luyn, Vaz, Willert, Willert, Williams   +65 more
core   +1 more source

Designer DNA‐Based Machines

SmartBot, EarlyView.
DNA machinery represents a burgeoning frontier at the intersection of robotics and nanotechnology, evolving from static nanostructure toward dynamic nanorobots. Here, the authors review the comprehensive research pipeline of designer DNA‐based nanomachines, covering the design, analysis, and fabrication. These programmable systems enable transformative
Yiquan An, Fan Wu, Yanyu Xiong, Cheng Zhang, Jian S. Dai, Lifeng Zhou   +5 more
wiley   +1 more source

Beyond bacterial defences: the role of lysozyme in cancer

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
Lysozyme (LYZ) is a multi‐functional secreted factor that encompasses both antibacterial and immunomodulatory functions. Emerging evidence highlights its complex role in tumour progression by directly influencing tumour cells and modulating the immune microenvironment.
Lei Wang, Qian Dong, Fuchu He, Zhiwen Gu, Aihua Sun   +4 more
wiley   +1 more source

Modular approach to select bacteriophages targeting Pseudomonas aeruginosa for their application to children suffering with cystic fibrosis [PDF]

, 2016
This review discusses the potential application of bacterial viruses (phage therapy) towards the eradication of antibiotic resistant Pseudomonas aeruginosa in children with cystic fibrosis (CF).
Bourkaltseva, Maria, Chesnokova, Elena, Kaplan, Alla, Krylov, Sergey, Krylov, Victor, Kulakov, Leonid, Magill, Damian, Pleteneva, Elena, Polygatsch, Olga, Shaburova, Olga   +9 more
core   +2 more sources

p62/SQSTM1 Condensation Modulates Mitochondrial Clustering to Participate in Mitochondrial Quality Control

Aging Cell, Volume 25, Issue 2, February 2026.
In normal PINK1/Parkin‐mediated mitophagy, unlike OPTN (the mitophagy receptor that mediates ATG8‐labeled autophagosome recruitment onto ubiquitinated mitochondria), p62 mediates the clustering of ubiquitinated mitochondria to form the “grape‐like” aggregates with ubiquitin.
Shan Sun, Jiaqi Xin, Yingping Zhang, Bojun Yang, Dan Su, Rui Ni, Qilian Ma, Ningning Li, Guoqiang Ma, Qiang Peng, Siqian Chen, Jochen H. M. Prehn, Kin Yip Tam, Hongfeng Wang, Zheng Ying   +14 more
wiley   +1 more source