Results 61 to 70 of about 7,517 (145)

Giant number fluctuations in microbial ecologies

open access: yes, 2012
Statistical fluctuations in population sizes of microbes may be quite large depending on the nature of their underlying stochastic dynamics. For example, the variance of the population size of a microbe undergoing a pure birth process with unlimited ...
Das, Dibyendu   +2 more
core   +1 more source

High‐throughput generic single‐entity sequencing using droplet microfluidics

open access: yesiMeta, Volume 4, Issue 6, December 2025.
We present Generic Single Entity Sequencing (GSE‐Seq), a droplet‐based workflow that generates monoclonal barcodes by one‐step PCR, performs dissolvable hydrogel‐enabled reactions for genome processing, and attaches barcodes during in‐droplet library preparation. Barcoded fragments are pooled and sequenced with PacBio long‐read sequencing. Barcodes are
Guoping Wang   +14 more
wiley   +1 more source

Exploring nucleo-cytoplasmic large DNA viruses in Tara Oceans microbial metagenomes [PDF]

open access: yes, 2013
Nucleo-cytoplasmic large DNA viruses (NCLDVs) constitute a group of eukaryotic viruses that can have crucial ecological roles in the sea by accelerating the turnover of their unicellular hosts or by causing diseases in animals. To better characterize the
Acinas, Silvia G.   +27 more
core   +1 more source

Phenotypical and Genomic Characterization of the Mollusk Pathogen Francisella halioticida

open access: yesMicrobiologyOpen, Volume 14, Issue 6, December 2025.
Phenotypic and genetic characterization of French isolates of Francisella halioticida and comparison with Canadian and Japanese strains. The study revealed similarities between FR22s and previous isolates but distinct differences with FR21. A major finding is the absence of the Francisella pathogenicity island in the less virulent isolate, FR22b ...
Hélène Bouras   +7 more
wiley   +1 more source

Advancing Tuberculosis Chemotherapy: Targeted Nanomedicines for the Mycobacterium TB Granuloma

open access: yesSmall, Volume 21, Issue 49, December 10, 2025.
This graphical abstract illustrates nanosystems used for targeted drug delivery into tuberculosis granulomas. It shows how targeting is influenced by size, pH, redox sensitivity, and surface charge. Various nanoparticles are incorporated with drugs to enhance penetration, stability, and release.
Shreya Ranjith Singh   +3 more
wiley   +1 more source

Filamentous phages as building blocks for reconfigurable and hierarchical self-assembly

open access: yes, 2017
Filamentous bacteriophages such as fd-like viruses are monodisperse rod-like colloids that have well defined properties: diameter, length, rigidity, charge and chirality. Engineering those viruses leads to a library of colloidal rods which can be used as
Gibaud, Thomas
core   +2 more sources

Viruses as living processes [PDF]

open access: yes, 2016
John Dupre University of Exeter Egenis Byrne House, St German's Road Exeter EX4 4PJ UK Guttinger University of Exeter Egenis Byrne House, St German's Road Exeter EX4 4PJ United KingdomThe view that life is composed of distinct entities with well-defined ...
Dupré, John, Guttinger, S
core   +1 more source

Immunomodulatory Biomaterials for Bone and Soft Tissue Chronic Inflammation Diseases

open access: yesSmall Science, Volume 5, Issue 12, December 2025.
This review analyzes immunomodulatory biomaterial strategies for treating chronic inflammatory disorders in bone and soft tissues. It explores emerging mechanisms for resolving inflammation while promoting tissue regeneration, offering insights for developing targeted immunotherapeutic approaches that bridge material science with immunology for ...
Yiming Li   +7 more
wiley   +1 more source

Synthetic Biology: A Bridge between Artificial and Natural Cells. [PDF]

open access: yes, 2014
Artificial cells are simple cell-like entities that possess certain properties of natural cells. In general, artificial cells are constructed using three parts: (1) biological membranes that serve as protective barriers, while allowing communication ...
Ding, Yunfeng, Tan, Cheemeng, Wu, Fan
core   +2 more sources

Antimicrobial prescribing guidelines for horses in Australia

open access: yesAustralian Veterinary Journal, Volume 103, Issue 12, Page 781-889, December 2025.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt   +18 more
wiley   +1 more source

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