Results 61 to 70 of about 455,666 (157)
Mapping protein–protein interactions by mass spectrometry
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu +4 more
wiley +1 more source
Abstract ClpXP and other AAA proteases maintain proteostasis and regulate cellular functions by degrading misfolded, incomplete, or regulatory proteins. ClpX recognizes substrates via unstructured degron sequences, typically located at the N‐ or C‐terminus. Although five classes of degrons are known, only recognition of the ssrA tag, a C‐motif‐1 degron,
Yifei Lyu +4 more
wiley +1 more source
Characterisation of a Novel Jumbo Lytic Aeromonas dhakensis Bacteriophage P19 and Its Endolysin
A jumbo, lytic myovirus phage P19 against multidrug‐resistant (MDR) Aeromonas dhakensis was isolated from river water. P19 demonstrated robust lytic activity, high thermal and pH stability (pH 6–10, up to 60°C), and no genes associated with lysogeny, virulence or antimicrobial resistance. ORF_358 of P19 encodes for T4‐type lysozyme.
Farhat Ansari, Vandan Nagar
wiley +1 more source
Aquatic probiotics are generally recognized as safe and nontoxic live bacterial preparations, primarily sourced from the culturing environment or directly from aquatic organisms. Upon entering the aquatic environment, these probiotics are capable of colonizing both the surface and internal compartments of aquatic organisms, thereby enhancing their ...
Hui Guan +10 more
wiley +1 more source
Distinct Phage‐Encoded Enzymes for Substitution of Deoxythymidine by Deoxyuridine in Phage Genomes
Distinct enzymes including dCTP deaminases (Dcds), dTMP phosphatases (Dtms), and dTTP pyrophosphatases (Dtt) are found to be responsible for dU‐DNA biosynthesis in the phages PBS1, DSS3_VP1, and PhiR1‐37. Both PhiR1‐37‐derived and synthetic dU‐DNA are resistant to cleavage by restriction enzymes and Cas12a nuclease targeting dT‐containing sites.
Yating Li +7 more
wiley +1 more source
Analyses of four new Caulobacter Phicbkviruses indicate independent lineages.
Bacteriophages with genomes larger than 200 kbp are considered giant phages, and the giant Phicbkviruses are the most frequently isolated Caulobacter crescentus phages.
K. Wilson, B. Ely
semanticscholar +1 more source
Comparative genomics presentation at Howard Hughes Medical Institute with Stephanie Priesing.
openaire +1 more source
Exploration Editors’ Favorite Research in 2025
Exploration, Volume 6, Issue 1, February 2026.
wiley +1 more source
A Giant Phage Taillike Particle of Clostridium Saccharoperbutylacetonicum ATCC 13564 [PDF]
Seiya Ogata +5 more
openaire +1 more source

