Results 21 to 30 of about 144 (122)

Signaling pathways in macrophages: molecular mechanisms and therapeutic targets

MedComm, Volume 4, Issue 5, October 2023., 2023
In this review, the authors introduce the research advances related to macrophage signaling pathways by first providing an overview of the basic physiology of macrophages and expound on the regulatory pathways within them. Then, the pathogenic effect of macrophages and the therapeutic strategies targeting macrophage signaling pathways are addressed in ...
Ming Li, Mengjie Wang, Yuanjia Wen, Hongfei Zhang, Guang‐Nian Zhao, Qinglei Gao   +5 more
wiley   +1 more source

The Reconstruction after a Giant Phyllodes Tumor Resection Using a DIEP Flap

Plastic and Reconstructive Surgery, Global Open, 2020
Summary:. A phyllodes tumor of the breast is a rare neoplasm, accounting for 0.3%–1% of all breast cancers. The size is 4–5 cm on average but sometimes the tumor grows more and involves the entire breast.
Yuki Tsuruta, MD, Ryo Karakawa, MD, Koya Majima, MD, Satoru Yamamoto, MD, Tomoyoshi Shibata, MD, Hidehiko Yoshimatsu, MD, Hiroki Miyashita, MD, Kenta Tanakura, MD, Tomoyuki Yano, MD, PhD   +8 more
doaj   +1 more source

The giant phyllodes tumor of the breast — a case report

Experimental Oncology, 2023
Summary. Phyllodes tumors are rare tumors of the breast, which are often misdiagnosed as fibroadenomas and difficult to treat with adjuvant therapy. Here, we present a case of a female patient with giant phyllodes tumor of the breast.
V V, Zaichuk, A A, Samusieva, M V, Diatel, M M, Plodiienko   +3 more
openaire   +2 more sources

Recurrent giant borderline phyllodes tumor: resection and breast reconstruction [PDF]

Revista Brasileira de Cirurgia Plástica
Phyllodes Tumor is a rare fibroepithelial neoplasm that represents 0.3 to 1% of all breast neoplasms. According to histopathologic classification, 12 to 26% are borderline type and approximately 15% of these tumors recur after surgical excision.
Elizbet Susan Montes-Madariaga, Brando Ortiz-Saavedra, Euler Altamirano-Farfan, Melissa Herencia-Anaya, Jimmy Pumamango-Cordova   +4 more
doaj   +1 more source

Pattern of MUC6 expression across 119 different tumor types: A tissue microarray study on 15 412 tumors

Pathology International, Volume 73, Issue 7, Page 281-296, July 2023., 2023
Abstract Mucin 6 (MUC6) is a secreted gel‐forming mucin covering the surfaces of gastrointestinal and other tissues. Published work demonstrates that MUC6 can also be expressed in several cancer types and can aid in the distinction of different tumor entities.
Sebastian Dwertmann Rico, Sebastian J. A. Schliesser, Natalia Gorbokon, David Dum, Anne Menz, Franziska Büscheck, Andrea Hinsch, Maximilian Lennartz, Clara von Bargen, Ahmed A. Bawahab, Andreas M. Luebke, Claudia Hube‐Magg, Christoph Fraune, Patrick Lebok, Till S. Clauditz, Frank Jacobsen, Guido Sauter, Ria Uhlig, Stefan Steurer, Sarah Minner, Andreas H. Marx, Ronald Simon, Eike Burandt, Doris Hoeflmayer, Till Krech, Christian Bernreuther   +25 more
wiley   +1 more source

Giant breast tumors: Surgical management of phyllodes tumors, potential for reconstructive surgery and a review of literature

World Journal of Surgical Oncology, 2008
Background Phyllodes tumors are biphasic fibroepithelial neoplasms of the breast. While the surgical management of these relatively uncommon tumors has been addressed in the literature, few reports have commented on the surgical approach to tumors ...
McKelvey Michael T, Gordillo Gayle, Patterson Cynthia C, Ramaswamy Bhuvaneswari, Liang Margaret I, Nuovo Gerard J, Carson William E   +6 more
doaj   +1 more source

GIANT PHYLLODES TUMOR OF THE PROSTATE

The Japanese Journal of Urology, 2007
A 55 year-old man complained dysuria and visited to our hospital. Physical examination showed firm large mass occupying whole abdomen. Computed tomography (CT) demonstrated a huge retroperitoneal tumor which compressed intestine, liver, kidney, and urinary bladder.
Kawamorita, Naoki, Inaba, Yasuo, Soma, Fumihiko, Katayama, Yousei, Mikami, Yoshiki   +4 more
openaire   +3 more sources

Protein posttranslational modifications in health and diseases: Functions, regulatory mechanisms, and therapeutic implications

MedComm, Volume 4, Issue 3, June 2023., 2023
The reversible and irreversible protein posttranslational modifications, such as acetylation, methylation, phosphorylation, ubiquitination, glycosylation, SUMOylation, and redox modifications, are essential regulators in organisms and cells. This work systematically summarizes the features, regulatory mechanisms, substrates, functions, and related ...
Qian Zhong, Xina Xiao, Yijie Qiu, Zhiqiang Xu, Chunyu Chen, Baochen Chong, Xinjun Zhao, Shan Hai, Shuangqing Li, Zhenmei An, Lunzhi Dai   +10 more
wiley   +1 more source

Transcatheter arterial chemoembolization improves the resectability of malignant breast phyllodes tumor with angiosarcoma component: a case report

BMC Surgery, 2019
Background A giant phyllodes tumor of the breast is a rare fibroepithelial lesion, and its treatment is controversial. Many case reports have reported performing skin graft reconstruction after tumor excision.
Chih-Yu Kuo, Shing-Huey Lin, Kuan-Der Lee, Sho-Jen Cheng, Jan-Show Chu, Shih-Hsin Tu   +5 more
doaj   +1 more source

Synchronous malignant phyllodes tumor with skin ulceration and invasive carcinoma as collision tumor

Indian Journal of Medical and Paediatric Oncology, 2017
Phyllodes tumor is a rare fibroepithelial biphasic tumor of the breast composed of hypercellular mesenchymal stroma and double-layered epithelial component, arranged in clefts with leaf-like projections.
Rajeshwari K Muthusamy, Sangita S Mehta
doaj   +1 more source