Results 151 to 160 of about 689,791 (288)

p.Asp58Val Hereditary Transthyretin Amyloidosis: A Case Report and Literature Review. [PDF]

Cureus
Ramnarain J, Hosking P, Gibbs S.
europepmc   +1 more source

Accelerating Luminescence in Nanostructures: Exploring the Physical Limits and Impact of Ultrafast Emission in Nanoscale Materials

Advanced Photonics Research, EarlyView.
This review highlights recent advances in accelerating luminescence in nanostructures through cooperative emission, resonator coupling, and nonlocal light–matter interactions. By unifying concepts such as excitonic superradiance, superfluorescence, and the plasmonic Purcell effect, it reveals physical limits of ultrafast emission and their potential ...
Masaaki Ashida, Koichi Okamoto, Takuya Matsuda, Hajime Ishihara   +3 more
wiley   +1 more source

How Does Adenine Form from Hydrogen Cyanide? [PDF]

J Am Chem Soc
Cappelletti M, Rahm M.
europepmc   +1 more source

Designing High Performance Organic Donor Molecules for Photovoltaics

Advanced Theory and Simulations, EarlyView.
Systematically tuning the fusion pattern and length of the π$\pi$‐bridge, along with adjusting the electron‐withdrawing (EW) strength of the terminal groups in small‐molecule donor A-π-Core-π$\text{A-}\pi \text{-Core-}\pi$‐A architectures, enables predictable modulation of the system's opto‐electronic properties.
Fabian Bauch, Chuan‐Ding Dong, Stefan Schumacher   +2 more
wiley   +1 more source

Theoretical View: Thermodynamics of the Saturation Dissolution of a Molecular (Solid) Dispersion of a Hydrophobic Molecule and Polymeric Surfactant in an Aqueous Solution. [PDF]

Int J Mol Sci
Poša M.
europepmc   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

Advanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva, Sara Duarte‐Silva, Pedro M. Martins, Beatriz Rodrigues, Débora Serrenho, Daniela Vilasboas‐Campos, Andreia Teixeira‐Castro, Julio Vieyto‐Nuñez, Joel Mieres‐Perez, Francisco Figueiredo, Martyna Podlasiak, Tatiana Van‐der‐Kellen, Joana Fraga, James Noble, Carter Lantz, Niki Sepanj, Daniela Monteiro‐Fernandes, Sara Guerreiro, Andreia Neves‐Carvalho, Joana Pereira‐Sousa, Frank‐Gerrit Klärner, Thomas Schrader, Joseph A. Loo, Annalisa Pastore, Elsa Sanchez‐Garcia, Gal Bitan, Ana Luísa Carvalho, Patrícia Maciel, Sandra Macedo‐Ribeiro   +28 more
wiley   +1 more source

Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression

Advanced Science, EarlyView.
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo, Xiaodong Chen, Haojia Wang, Jiying Zhou, Peiying Lu, Jiangying Liu, Keyan Chai, Jingyuan Zhang, Siyun Yang, Shan Lu, Yifei Gao, Zhengsen Jin, Xiaoyu Tao, Zhongdong Hu, Qinglin Li, Jiarui Wu   +15 more
wiley   +1 more source

Hydrolysis mechanisms for A-series (Novichok) nerve agents at different pH V and computational simulant screening. [PDF]

RSC Adv
Jia J, Duan W, Li Q, Xu X, Tian Z, Zhang Z.   +5 more
europepmc   +1 more source

A Virtual Clinical Trial of Psychedelics to Treat Patients With Disorders of Consciousness

Advanced Science, EarlyView.
Disorders of consciousness after severe brain injury are marked by reduced complexity of brain activity and limited treatment options. Using personalized whole‐brain models, this study shows that simulated lysergic acid diethylamide (LSD) and psilocybin shift patient brain dynamics closer to criticality.
Naji L.N. Alnagger, Paolo Cardone, Charlotte Martial, Yonatan Sanz Perl, Iván Mindlin, Jacobo D Sitt, Leor Roseman, Robin Carhart‐Harris, David Nutt, Pablo Mallaroni, Natasha Mason, Johannes G Ramaekers, Vincent Bonhomme, Steven Laureys, Gustavo Deco, Olivia Gosseries, Pablo Núñez, Jitka Annen   +17 more
wiley   +1 more source

Considerations for the use of targeted fluorescence contrast agents to detect circulating cancer cell populations with diffuse <i>in vivo</i> flow cytometry. [PDF]

J Biomed Opt
Pace JS, Matheson G, Malankar G, Wang L, Wong MH, Gibbs SL, Niedre M.   +6 more
europepmc   +1 more source