Results 81 to 90 of about 759,190 (258)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
The influence of relationship beliefs on gift giving
People have fundamental beliefs about what constitutes a good relationship, known as implicit theories of relationship, where some people have destiny beliefs whereas others have growth beliefs. People with destiny beliefs believe that potential partners
Rai Dipankar +3 more
doaj +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
A Gift is not Always a Gift: Gift Exchange in a Voucher Experiment [PDF]
Different from traditional gift exchange experiments, we study a field experiment where a random subsample of participants in the Swiss Labor Force Survey was sent vouchers to be used in adult training courses.
Dolores Messer +2 more
core
This article examines gift-giving during Ottoman Sultan Abdul Aziz’s State visit to Britain in July 1867. An exceptional occasion in itself – for an Ottoman Sultan had never left his Empire in peacetime or ever would again –, the visit offers an ...
Stéphanie Prévost
doaj +1 more source
Okulda Hediye Sürecine İlişkin Yönetici ve Öğretmen Görüşleri
Bu araştırmada Türkiye’deki kamu ve özel okullarda öğrenci ve velilerin öğretmenlere hediye verme davranışlarının derinlemesine incelenmesi amaçlanmıştır.
İnayet Aydın +3 more
doaj
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Models for voluntary provision of public goods predict free riding is rational unless the model includes a motive for the act of giving referred to as a “warm glow” in the literature.
Michael McKee, Michael Jones
core
Feeling Poor, Acting Stingy: the effect of money perception on charitable giving [PDF]
In research on philanthropy, much attention has been given to the impact of the actual economic costs of giving. This paper argues that the perceived psychological costs of giving should also be taken into consideration when seeking to understand ...
Pamala Wiepking +5 more
core +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source

