Results 91 to 100 of about 1,628,791 (312)

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Dono ed economie altre: per un nuovo contratto sociale

open access: yesEtnoAntropologia, 2014
The article focuses on the recent debate, about gift and the non-market economies, born especially around the new lecture of classical texts of Marcel Mauss and Karl Polanyi.
Antonietta Di Vito
doaj   +1 more source

Fighting Through Britain. The “Gift Dimension” of Keynes's Quest for a New Global Order [PDF]

open access: yes
Dissatisfied with both Skidelsky's “Fighting for Britain” approach to Keynes's quest for a new global order and its specular competitor, the “Figthing despite Britain” view, we explore the possibility of a “Fighting through Britain” approach to the issue.
Mario A. Cedrini
core  

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

The Gifted Student: Gifts and Talents Development

open access: yesElementa
The concept of giftedness has evolved significantly over time. Today, it still lacks a singular and precise definition, but it is continually evolving. One notable model found in the literature is the Differentiated Model of Giftedness and Talent (DMGT ...
Roberta Baldini   +1 more
doaj   +1 more source

Words Speak Louder Than Money [PDF]

open access: yes
Should one use words or money to foster trust of the other party if no means of enforcing trustworthiness are available? This paper reports an experiment studying the effectiveness of two types of mechanisms for promoting trust: a costly gift and a ...
Maroš Servátka   +2 more
core  

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

SCIENCE, RELIGION, AND ETHICS: A RESPONSE TO MICHAEL J. REISS

open access: yesZygon, 2019
The respondent agrees with Michael Reiss's general diagnosis of the rudderless state of ethics in our modern society, but not with all of his account of its causes or possible solutions.
doaj   +2 more sources

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

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