Results 131 to 140 of about 954 (249)
Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel +5 more
wiley +1 more source
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter +20 more
wiley +1 more source
Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman +3 more
wiley +1 more source
ABSTRACT Objectives This laboratory study investigated the effect of two different retentive heights of Ti‐base abutments (3.5 and 5.5 mm) and crown heights (13 and 16 mm) on the load at failure and survival of monolithic zirconia implant‐supported crowns replacing a maxillary central incisor.
Esha Zahid +5 more
wiley +1 more source
On the Influence of Ultimate Number of Cycles on Lifetime Prediction for Compression Springs Manufactured from VDSiCr Class Spring Wire. [PDF]
Geilen MB, Klein M, Oechsner M.
europepmc +1 more source
Development of an ultrasonic fatigue testing system for gigacycle fatigue [PDF]
Paul Ilie, Xavier Lesperance, Ayhan Ince
openaire +1 more source
A new approach for predicting the fatigue strength of steels and aluminum alloys in high & giga cycle regimes [PDF]
Since 1990s various methods have been proposed by researchers to estimate the fatigue strengths of metals at gigacycle fatigue regime (number of cycles > 108).
Bandara, A.M.A.C.S. +3 more
core
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton +4 more
wiley +1 more source

