Results 41 to 50 of about 238 (221)

Ultrasonic fatigue tests at high temperature on an austenitic steel

open access: yesPropulsion and Power Research, 2012
The objective of this paper is to study the gigacycle fatigue behavior of an austenitic steel at temperatures of 600 °C and 700 °C under fully reverse loading (R=−1).
D. Wagner   +3 more
doaj   +1 more source

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng   +10 more
wiley   +1 more source

Ultrasonic Resonance Fatigue Testing of 6082 Aluminum Alloy

open access: yesMetals
This study explores the fatigue properties of EN AW-6082-T6 aluminum alloy in the gigacycle range (106–109 cycles), using ultrasonic resonance fatigue testing at 20 kHz in a push–pull mode with a symmetric load cycle (R = −1).
Diyan M. Dimitrov   +3 more
doaj   +1 more source

Lightweight, Elastic Ceramic Fabrics for Broadband Electromagnetic Absorption and High Temperature Thermal Insulation

open access: yesAdvanced Science, EarlyView.
This study reports lightweight, elastic ceramic fabrics with broadband electromagnetic absorption (EAB = 9.8 GHz) and high‐temperature thermal insulation, enabled by precise microstructural control during ultrafast high‐temperature sintering (UHS), which induces the precipitation of defect‐rich t‐ZrO2 nanograins and turbostratic C nanoclusters.
Jiahao Yang   +9 more
wiley   +1 more source

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

open access: yesAdvanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu   +7 more
wiley   +1 more source

Properties of the Fine Granular Area and Postulated Models for Its Formation during Very High Cycle Fatigue—A Review

open access: yesApplied Sciences, 2020
Understanding the mechanisms leading to very high cycle fatigue is necessary to make predictions about the behavior under various conditions and to ensure safe design over the whole lifetime of high-performance components.
Jan Patrick Sippel, Eberhard Kerscher
doaj   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

open access: yesAdvanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo   +18 more
wiley   +1 more source

The upper limit extension of loading frequency in the rotating bending fatigue test

open access: yesNihon Kikai Gakkai ronbunshu, 2017
Fatigue property in gigacycle regime is focused as an important subject in recent years. In such a long-life region, a tremendous long period is required to perform the fatigue tests. In order to overcome this difficulty, special types of fatigue testing
Taizoh YAMAMOTO   +2 more
doaj   +1 more source

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

open access: yesAdvanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song   +5 more
wiley   +1 more source

A Closed‐Loop Framework for Inverse Design: Dynamic Training and Intelligent Optimization for Heterostructured Materials

open access: yesAdvanced Science, EarlyView.
To accelerate the inverse design of heterostructured metal matrix composites, a closed‐loop scientific machine learning framework integrates continual learning prediction with NSGA‐II‐PMCP optimization. The framework maps microstructural descriptors to strength, toughness, and modulus, expands high‐quality Pareto solutions, and guides experimentally ...
Zhiyan Zhong   +11 more
wiley   +1 more source

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