Results 211 to 220 of about 532,493 (260)

Changes in effectiveness and safety in patients with Lennox–Gastaut syndrome transitioning from the fenfluramine randomized controlled trial to open‐label extension study

open access: yesEpilepsia Open, EarlyView.
This graphical abstract provides an overview of the content from this post hoc analysis describing the trajectories of fenfluramine effectiveness and safety, along with dose changes over time, in patients with Lennox‐Gastaut syndrome. Abstract In the phase 3 randomized controlled trial (RCT; NCT03355209) of fenfluramine in Lennox–Gastaut syndrome (LGS),
Rima Nabbout   +14 more
wiley   +1 more source

Efficacy and safety of fenfluramine in Dravet syndrome: The impact of patient clinical characteristics

open access: yesEpilepsia Open, EarlyView.
This graphical abstract provides an overview of the content from this post hoc analysis evaluating the efficacy and safety of fenfluramine in patients with Dravet syndrome stratified by age, number of previously attempted antiseizure medications, and SCN1A pathogenic variant status using data pooled from the three pivotal randomized controlled trials ...
Rima Nabbout   +20 more
wiley   +1 more source

Evaluation of Nutritional and Bioactive Compounds in Tea and Botanical Marc Following Industrial Liqueur Maceration

open access: yesFood Chemistry International, EarlyView.
Industrial botanical marc retained valuable phytochemicals, antioxidants, catechins, and caffeine after ethanol maceration, with composition varying by botanical source and processing. These underutilized by‐products represent promising, safe, and sustainable feedstocks for recovering bioactive compounds for food, nutraceutical, and functional ...
Veronika Šimora   +7 more
wiley   +1 more source

Valorization of Citrus Waste for Recovery of Nutritional and Bioactive Compounds: A Comprehensive Review

open access: yesFuture Postharvest and Food, EarlyView.
The various citrus wastes, including the citrus fruit peels, pulp remaining after extraction of juice, and seeds, are the sources of bioactive compounds. The waste parts of oranges, lemons, limes, grapefruits, and mandarins contain the bioactive compounds, flavonoids, ascorbic acid, essential oils, and carotenoids.
Monika   +4 more
wiley   +1 more source

Postoperative Hemoglobin and Transfusion Rates Do Not Influence Revision of Head and Neck Free Flap in a Cohort of 259 Patients

open access: yesHead &Neck, EarlyView.
ABSTRACT Introduction Recent literature advocates restrictive transfusion thresholds (Hb < 7 g/dL). The aim of this study was to evaluate if postoperative hemoglobin levels and transfusions influence Free Flap Revision (FFR). Methods This single center retrospective study included all patients who underwent head and neck surgery with free flap ...
Olivier Gilbert   +9 more
wiley   +1 more source

Diffuse Large B-Cell Lymphoma Masquerading as Cholangiocarcinoma in a Young Adult. [PDF]

open access: yesACG Case Rep J
Gil-Lopez F   +8 more
europepmc   +1 more source

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