Results 91 to 100 of about 57,539 (299)

The Impact of a Forced Non-Medical Switch of Inhaled Respiratory Medication Among Patients with Asthma or Chronic Obstructive Pulmonary Disease: A Patient Survey on Experience with Switch, Therapy Satisfaction, and Disease Control

Patient Preference and Adherence, 2020
Ileen Gilbert,1 Keiko Wada,2 Chakkarin Burudpakdee,2 Chirag Ghai,2 Laren Tan3 1AstraZeneca, Wilmington, DE, USA; 2IQVIA, Falls Church, VA, USA; 3Loma Linda University Health, Department of Medicine, Division of Pulmonary, Critical Care, Hyperbaric ...
Gilbert I, Wada K, Burudpakdee C, Ghai C, Tan L   +4 more
doaj  

Human Gut Bacteria and Lipidic Nanoparticles: Particle Composition Predicts Structural Transformation and Bacterial Biocompatibility

Advanced Functional Materials, EarlyView.
Lipidic nanoparticles (LNPs) were incubated with 21 gut bacteria frequently associated with the human microbiome. SAXS revealed that ∼75% of tested species induced structural transformations in monoolein LNPs, whereas phytantriol and phospholipid formulations remained unaffected.
Jonathan Caukwell, Emily L. Gulliver, Livia Salvati Manni, Frithjof Herb, Caitlin Welsh, Samuel C. Forster, Andrew J. Clulow, Wye‐Khay Fong   +7 more
wiley   +1 more source

Nutritional Characterisation of Childhood Chronic Kidney Disease: Trace Element Malnutrition in Paediatric Renal Disease (TeMPeReD) Study

Background/Objectives: In chronic kidney disease (CKD), poor nutrition is associated with poorer clinical outcomes. There are limited data on milder stages of childhood CKD.
Gilbert, Rodney, Wootton, Stephen, Matthew J. Harmer, Stephen A. Wootton, Harmer, Matthew James, Rodney D. Gilbert, Caroline E. Anderson, Anderson, Caroline   +7 more
core   +1 more source

Risk prioritization of pork supply movements during an FMD outbreak in the US - Data and Materials

, 2016
The Data.csv file contains the raw survey responses (location information collected by Qualtrics has been removed). Information about the variables and value labels can be found in the DataDictionary.txt file.
Tim Snider (17479428), Thomas A. Lindsay (17479431), Gilbert R. Patterson (17479422), Fernando Sampedro (17479437), Sampedro, Fernando, Patterson, Gilbert R, Davies, Peter, Peter Davies (95719), Tim Goldsmith (17479434), Alicia Hofelich Mohr (17479425), Hofelich Mohr, Alicia, Lindsay, Thomas A, Snider, Tim, Goldsmith, Tim   +13 more
core   +1 more source

Protective effect of elevated bilirubin levels on cardiovascular disease in patients with Gilbert syndrome

Türk Kardiyoloji Derneği Arşivi, 2015
Emre Gürel, Mustafa Kürşat Tigen
doaj   +1 more source

A Dual‐Bioresponsive and Programmable Microneedle Matrix as a Bioinspired Coupler for Orchestrating Diabetic Bone Regeneration

Advanced Materials, EarlyView.
This project developed a smart bandage‐like patch (a microneedle array) for repairing diabetic bone damage. It intelligently senses signals from infection and inflammation, then releases its medicines in a specific, timed sequence: first an antibacterial agent, then an anti‐inflammatory agent, and finally growth factors.
Yu Wang, Rui Chen, Yu Chen, Haowen Lu, Yuchen Qian, Zhiheng Gao, Zheming Shen, Xiaofei Zheng, Huilin Yang, Jun Zou, Yusen Qiao   +10 more
wiley   +1 more source

Minimally Invasive Delivery of Optical Nanosensors Using Injectable Hydrogels

Advanced Materials Interfaces, EarlyView.
Injectable peptide hydrogels offer a minimally invasive delivery platform for single‐walled carbon nanotube (SWCNT)‐based near‐infrared fluorescent sensors, enabling real‐time measurement of drug concentrations. Encapsulated SWCNTs show a dose‐dependent fluorescence response across physiologically relevant concentrations and retain their fluorescence ...
Shirel Kleiner, Gili Bisker
wiley   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source

Clinical Association Between Psychotic Symptoms and the Gilbert Syndrome: A Case Report

Neuropsychiatric Investigation
Modern research in psychiatry is increasingly focusing on the possible identification of potentially useful biomarkers for early and differential diagnosis and patient-tailored therapy.
Balaswamy Reddy, Alessandra Nocera, Renato de Filippis, Soumitra Das   +3 more
doaj  

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

Advanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel, Sofia Kokkaliari, Qiwen Gao, Jinjing Chen, Larissa Costa de Almeida, Srinivasarao Tenneti, Derek A. Leas, Eli Levit, Lewis S. Alexander, Khalil A. Abboud, Pingrong Wei, Michael D. Cameron, James R. Rocca, Ranjala Ratnayake, Donna D. Zhang, Hendrik Luesch, Robert W. Huigens III   +16 more
wiley   +1 more source