Results 101 to 110 of about 1,555,906 (271)

Programmable three‐state nanoreactor for spatiotemporally controlled tumor therapy

open access: yesBMEMat, EarlyView.
The OMVs are shielded with a biocompatible Da–Ca shell, which prolongs its circulation period and promotes intratumoral accumulation. Importantly, the biocompatible Da–Ca shell can be controllably disintegrated in tumor microenvironment by using laser irradiation, generating in situ hyperthermia and releasing Ca2+.
Guihong Lu   +12 more
wiley   +1 more source

Building Confidence in Hybrid Anatomy Learners

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Human Anatomy's challenging content load can often undermine student confidence. We investigated how confidence correlates with academic performance and which confidence building strategies are perceived as impactful on academic performance.
Reivian Berrios Barillas   +4 more
wiley   +1 more source

Temporal Trends and Prognosis in Rotational Atherectomy: A Comparison of Contemporary and Traditional Eras

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Rotational atherectomy (RA) has undergone considerable technical modernization in recent years. This study evaluated whether RA performed in the contemporary era was associated with superior cardiovascular outcomes compared with the traditional era. Aims To compare the clinical characteristics and cardiovascular outcomes of patients
Ravi Vazirani   +15 more
wiley   +1 more source

Portrait with biographical detail of Joyce Gilbert

open access: yes, 1976
Portrait with biographical detail of Joyce Gilbert. Centre'.

core  

How to Optimize Healthy Volunteer Screening and Enrolment in Clinical Trials: A Qualitative and Quantitative Approach to Evaluate Processes and Healthy Volunteers' Perceptions

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Healthy volunteers (HVs) are essential for phase I trials, yet their recruitment and screening remain resource‐intensive and ethically complex. High screening failure (SF) rates highlight the need to evaluate and understand all aspects of the enrolment processes. We analyzed SF patterns in a large German HV cohort and explored participants' motivations,
Evelyn Krohmer   +10 more
wiley   +1 more source

Toward Fit‐for‐Purpose Data for Drug Assessment in Non‐small Cell Lung Cancer: A Core Dataset

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Considering the high unmet medical need in people with non‐small cell lung cancer (NSCLC), the drug assessment for targeted therapies often rely on small populations and single‐arm trials, challenging the evaluation by regulatory authorities, health technology assessment bodies (HTAb), and clinicians.
Geeske F. Grit   +6 more
wiley   +1 more source

Hanseniasis With Gilbert′s Syndrome : A Therapeutic Dilemma?

open access: yesIndian Journal of Dermatology, 2000
Therapeutic dilemma often arises in leprosy patients developing jaundice as most of the anti-hanseniasis medicines are hepatotoxic. One 26 year old lady and another 21 year old male having paucibacillary leprosy developed signs of jaundice after onset of
Ghosh Sanjay
doaj  

Association of single nucleotide variants of the SLCO1B1 gene with the Gilbert syndrome phenotype

open access: yesБюллетень сибирской медицины
The aim of the study is to investigate the association of rs2306283 and rs4149056 variants of the SLCO1B1 gene with benign unconjugated hyperbilirubinemia. Materials and methods. A case-control study design was employed.
A. A. Ivanova   +7 more
doaj   +1 more source

Modifiable Transdiagnostic Risk and Protective Factors as Potential CBT Augmentation Targets for Eating Disorders: An Updated Umbrella Review

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective A focus on transdiagnostic targets is one of the key strategies for developing effective, efficient, and scalable treatments for mental health conditions. We conducted an umbrella review of recent meta‐analyses (August 2022 to May 2026) to update our understanding of critical transdiagnostic intervention targets that could inform ...
Yuan Zhou   +2 more
wiley   +1 more source

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