Results 221 to 230 of about 1,555,906 (271)
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BMJ, 2011
A 22 year old man presents with a resolving episode of mild jaundice after an influenza-like illness. He reports a previous episode after an appendicectomy, which also resolved spontaneously, but he is worried about the implications of this recurrence. Biochemical records from his surgical admission show a slightly raised bilirubin concentration of 48 ...
Lee C, Claridge +3 more
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A 22 year old man presents with a resolving episode of mild jaundice after an influenza-like illness. He reports a previous episode after an appendicectomy, which also resolved spontaneously, but he is worried about the implications of this recurrence. Biochemical records from his surgical admission show a slightly raised bilirubin concentration of 48 ...
Lee C, Claridge +3 more
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Baillière's Clinical Gastroenterology, 1989
While Gilbert's syndrome is extremely common and benign, its pathogenesis may not be as straightforward as once believed. It has been used as a model to examine aberrations of virtually every step in bilirubin metabolism. The clinical hallmarks are of a hereditary, chronic, mild unconjugated hyperbilirubinaemia.
K J, Watson, J L, Gollan
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While Gilbert's syndrome is extremely common and benign, its pathogenesis may not be as straightforward as once believed. It has been used as a model to examine aberrations of virtually every step in bilirubin metabolism. The clinical hallmarks are of a hereditary, chronic, mild unconjugated hyperbilirubinaemia.
K J, Watson, J L, Gollan
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Overview of Gilbert’s syndrome
Drug and Therapeutics Bulletin, 2019### Key learning points Gilbert’s syndrome (GS) is a benign hereditary disorder of bilirubin conjugation resulting in an isolated, elevated blood level of unconjugated bilirubin.1 GS affects 2%–10% of the Caucasian population in the Western world.2,3 The inheritance pattern for GS is commonly autosomal recessive, but can be dominant as well; however ...
D, King, M J, Armstrong
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International Journal of Nursing Education and Research, 2021
Gilbert's syndrome (GS) is a benign condition that does not progress to chronic liver disease or fibrosis. GS diagnosis should be considered in patients with chronic elevation of unconjugated bilirubin. In these patients the presence of hemolysis and other diseases of the liver should be excluded.
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Gilbert's syndrome (GS) is a benign condition that does not progress to chronic liver disease or fibrosis. GS diagnosis should be considered in patients with chronic elevation of unconjugated bilirubin. In these patients the presence of hemolysis and other diseases of the liver should be excluded.
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Gastroenterology Nursing, 1996
Two or three times a year, a healthy patient (> 1 year old) with mild unconjugated hyperbilirubinemia as the only abnormality on routine liver function testing will be referred to the gastroenterologist. A diagnosis of Gilbert Syndrome (GS) is made, and the patient may or may not be seen in the clinic or office because GS is a benign condition.
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Two or three times a year, a healthy patient (> 1 year old) with mild unconjugated hyperbilirubinemia as the only abnormality on routine liver function testing will be referred to the gastroenterologist. A diagnosis of Gilbert Syndrome (GS) is made, and the patient may or may not be seen in the clinic or office because GS is a benign condition.
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Pathogenesis of Gilbert's syndrome
European Journal of Clinical Investigation, 1981Chronic unconjugated hyperbilirubinaemia is a frequent finding. Overt haemolysis, dyserythropoiesis and other diseases including hepatobiliary, cardiac and thyroid disorders [1] have to be ruled out. The diagnosis of Gilbert's syndrome is then usually put forward if the history and clinical and laboratory investigations are normal. This benign disorder
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European journal of pediatrics, 2012
Gilbert syndrome is a common autosomal dominant hereditary condition with incomplete penetrance and characterized by intermittent unconjugated hyperbilirubinemia in the absence of hepatocellular disease or hemolysis. In patients with Gilbert syndrome, uridine diphosphate-glucuronyl transferase activity is reduced to 30% of the normal, resulting in ...
Andrew, Fretzayas +3 more
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Gilbert syndrome is a common autosomal dominant hereditary condition with incomplete penetrance and characterized by intermittent unconjugated hyperbilirubinemia in the absence of hepatocellular disease or hemolysis. In patients with Gilbert syndrome, uridine diphosphate-glucuronyl transferase activity is reduced to 30% of the normal, resulting in ...
Andrew, Fretzayas +3 more
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Gilbert's syndrome is not associated with HELLP syndrome
BJOG: An International Journal of Obstetrics & Gynaecology, 2001The HELLP syndrome has been associated with postpartum unconjugated hyperbilirubinaemia. Several types of disorders cause unconjugated hyperbilirubinaemia, Gilbert's syndrome being the most common. In Caucasians a genetic defect in the TATA box of the promotor region of the gene encoding for bilirubin UDP‐glucuronyltransferase is tightly associated ...
Zusterzeel, P L +4 more
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Gilbert's Syndrome—Does It Exist?
Acta Medica Scandinavica, 1988Abstract. Liver function tests and prevalence of different symptoms generally said to occur in Gilbert's syndrome were analysed in male conscripts and in male and female participants in two cross‐sectional population studies in Göteborg, in total 2395 subjects. The serum bilirubin levels showed a skew distribution without bimodality.
R, Olsson +6 more
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UDP-Glucuronosyltransferase in gilbert’s syndrome
Pathology, 1996The diagnosis of Gilbert's syndrome, a condition characterised by mild jaundice related to chronic unconjugated hyperbilirubinemia, is often presumptive and the pathogenesis is incompletely understood. It would be of interest to develop an immunohistochemical staining method to confirm a diagnosis of Gilbert's syndrome.
H S, Debinski +5 more
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