Results 41 to 50 of about 9,382,182 (359)

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

Hepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou, Yongkun Sun, Wen Zhang, Jiajia Yuan, Zhi Peng, Wei Wang, Jifang Gong, Lin Yang, Yanshuo Cao, Hong Zhao, Chao Chen, Weifeng Wang, Lin Shen, Aiping Zhou   +13 more
wiley   +1 more source

The “Gum–Gut” Axis in Inflammatory Bowel Diseases: A Hypothesis-Driven Review of Associations and Advances

Frontiers in Immunology, 2021
In modern medicine, the oral cavity has often been viewed as a passive conduit to the upper airways and gastrointestinal tract; however, its connection to the rest of the body has been increasingly explored over the last 40 years.
K. Byrd, Ajay S. Gulati
semanticscholar   +1 more source

Tetracycline Actions Relevant to Rosacea Treatment [PDF]

, 2009
Until today, the pathogenesis of rosacea is not known in detail. Yet in recent years evidence has been accumulating that rosacea with its common symptoms such as inflammatory lesions, erythema, telangiectasia, phymatous changes, and ocular symptoms is of
Korting, Hans Christian, Schöllmann, C.
core   +1 more source

Identification of Gingival Crevicular Fluid Sampling, Analytical Methods, and Oral Biomarkers for the Diagnosis and Monitoring of Periodontal Diseases: A Systematic Review

Disease Markers, 2016
Background. Several studies in the last decades have focused on finding a precise method for the diagnosis of periodontal disease in its early stages. Aim.
Z. N. Majeed, K. Philip, A. Alabsi, S. Pushparajan, D. Swaminathan   +4 more
semanticscholar   +1 more source

Lactoferrin. A natural glycoprotein involved in iron and inflammatory homeostasis [PDF]

, 2017
Human lactoferrin (hLf), an iron-binding multifunctional cationic glycoprotein secreted by exocrine glands and by neutrophils, is a key element of host defenses.
Cutone, Antimo, Lepanto, Maria Stefania, Paesano, Rosalba, Rosa, Luigi, Valenti, Piera   +4 more
core   +2 more sources

Treatment of Porphyromonas gulae infection and downstream pathology in the aged dog by lysine-gingipain inhibitor COR388. [PDF]

, 2020
COR388, a small-molecule lysine-gingipain inhibitor, is currently being investigated in a Phase 2/3 clinical trial for Alzheimer's disease (AD) with exploratory endpoints in periodontal disease.
Arastu-Kapur, Shirin, Araujo, Joseph, De Lannoy, Ines AM, Dominy, Stephen S, Ermini, Florian, Haditsch, Ursula, Holsinger, Leslie J, Lynch, Casey, Nguyen, Mai, Raha, Debasish, Ryder, Mark I   +10 more
core   +1 more source

LipStaT® Surgery, A Novel Technique for the Treatment of Gummy Smile: Case Report

Acta Odontológica Colombiana, 2020
Introduction: The lip stabilization technique (LipStaT®) is a novel surgical approach for the management of gummy smile. It is an outpatient technique, minimally invasive, with low risk of morbidity and low incidence of complications.
Isabella Manzur Villalobos, Eilien Gisek Tovío Martínez, Eliana Marcela Guzmán Menco, Adel Martínez Martínez   +3 more
doaj   +1 more source

Transcriptomes in Healthy and Diseased Gingival Tissues [PDF]

Journal of Periodontology, 2008
Background: Clinical and radiographic measures are gold standards for diagnosing periodontitis but offer little information regarding the pathogenesis of the disease. We hypothesized that a comparison of gene expression signatures between healthy and diseased gingival tissues would provide novel insights in the pathobiology of periodontitis and would ...
Ryan T, Demmer, Jan H, Behle, Dana L, Wolf, Martin, Handfield, Moritz, Kebschull, Romanita, Celenti, Paul, Pavlidis, Panos N, Papapanou   +7 more
openaire   +2 more sources

Dental plaque–induced gingival conditions

Journal of Clinical Periodontology, 2018
OBJECTIVE This review proposes revisions to the current classification system for gingival diseases and provides a rationale for how it differs from the 1999 classification system.
S. Murakami, B. Mealey, A. Mariotti, I. Chapple   +3 more
semanticscholar   +2 more sources

Periodontal manifestations of systemic diseases and developmental and acquired conditions: Consensus report of workgroup 3 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions.

The Journal of Periodontology, 2018
BACKGROUND A variety of systemic diseases and conditions can affect the course of periodontitis or have a negative impact on the periodontal attachment apparatus.
S. Jepsen, J. Caton, J. Albandar, N. Bissada, P. Bouchard, P. Cortellini, K. Demirel, M. de Sanctis, C. Ercoli, Jingyuan Fan, N. Geurs, F. Hughes, Lijian Jin, A. Kantarcı, E. Lalla, P. Madianos, D. Matthews, M. McGuire, M. Mills, P. Preshaw, M. Reynolds, A. Sculean, C. Susin, N. West, K. Yamazaki   +24 more
semanticscholar   +2 more sources