Results 141 to 150 of about 13,464 (270)

Achilles tenocytes from diabetic and non diabetic donors exposed to hyperglycemia respond differentially to inflammatory stimuli and stretch

Journal of Anatomy, EarlyView.
Scheme depicting the experimental set up of the study. Achilles tendons and tenocytes were isolated from heterozygous (fa/+, non diabetic: non DMT2) and homozygous (fa/fa, diabetic: DMT2) Zucker Diabetic Fatty (ZDF) rats. Tendon degeneration, collagen type 1 alpha 1 chain (COL1A1) and alpha smooth muscle actin (αSMA) expression was determined in rat ...
Nils Fleischmann, Sarah Hofmann, Clemens Gögele, Eva Frank, Christian Werner, Maria Kokozidou, Bernd Hoffmann, Jens Konrad, Gundula Schulze‐Tanzil   +8 more
wiley   +1 more source

Periodontitis and metabolic diseases (diabetes and obesity): Tackling multimorbidity

Periodontology 2000, EarlyView., 2023
Abstract Noncommunicable diseases (NCDs) are multifactorial, long‐term, chronic conditions that represent a burden to health‐care systems worldwide as they can only be controlled rather than cured; hence, they require long‐term care. With the exponential increase in NCDs, the occurrence of individuals presenting with more than one chronic disease is ...
Crystal Marruganti, Jean E. Suvan, Francesco D'Aiuto   +2 more
wiley   +1 more source

Prevalence of Oral Alterations and Correlation Between Oral and Cutaneous Neurofibromas in Neurofibromatosis Type 1: A Retrospective Case–Control Study

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Objective The aim of this study was to determine the prevalence of oral alterations detectable through physical examination in NF1 individuals. Additionally, we assessed the correlation between the number of oral and cutaneous neurofibromas. Design This retrospective study evaluated oral alterations in individuals with and without NF1.
Pâmella de Pinho Montovani, Gabriela Pizão Werneck Moreira da Costa, Rafaela Elvira Rozza‐de‐Menezes, Karin Soares Cunha   +3 more
wiley   +1 more source

Investigation of the Telomere Length in PERI‐Implant Oral Mucosa Cells

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background The biological effects of dental implants on peri‐implant tissues have been widely investigated. Recent reports of oral squamous cell carcinoma (OSCC) cases adjacent to dental implants have raised concerns regarding the potential impact of implant materials on cellular aging and oncogenic transformation.
Fernando Costa Giffoni, Thaís Ellen Chaves Gomes, Priscila Nazaré de Souza, Paula Valente e Silva, Luiz Alexandre Viana Magno, Amanda Lage Cândido, Marcelo Faria Lasmar, Sebastião Guilherme de Oliveira Neto, Marcus Vinicius Lucas Ferreira, Thiago Moreira Gonçalves Araujo, Luara Isabela dos Santos, Bruno Ramos Chrcanovic, Ricardo Santiago Gomez, Roberta Rayra Martins‐Chaves   +13 more
wiley   +1 more source

Predicting Malignant Transformation in Oral Leukoplakia: A Multilayer Perceptron Approach Incorporating Clinicopathological Features and DNA Content

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Oral leukoplakia (OL) is a potentially malignant disorder of the oral mucosa. Accurate prediction of malignant transformation (MT) remains a clinical challenge. This study aimed to develop and evaluate a machine learning model that integrates histopathological, demographic, and DNA content features to predict MT risk in OL.
Guilherme Iani Pontes, Anna Luíza Damaceno Araújo, Andresa Borges Soares, Saman Warnakulasuriya, André Luis Santana de Freitas, Caroline Gennari Stevão, Marcelo Sperandio, Matheus Cardoso Moraes   +7 more
wiley   +1 more source

Langerhans cell histiocytosis: current concepts in dentistry and case report [PDF]

, 2016
Langerhans cell histiocytosis (LCH), which is a rare granulomatous pediatric disease of unknown etiology, is characterized by the idiopathic proliferation and accumulation of abnormal and clonal Langerhans cells or their ...
Alejo-Gonzalez, Francisco, Garrocho Rangel, Arturo, Pozos Guillén, Amaury de Jesús, Ramos-Gutierrez, Efraín, Ruiz Rodríguez, Socorro   +4 more
core  

Tissue Perfusion and Biomarkers Assessment Following Root Coverage Procedures

Journal of Periodontal Research, EarlyView.
Gingival recessions treated with a collagen matrix loaded with rhPDGF showed significantly greater early tissue perfusion compared to sites treated without the growth factor. Early tissue perfusion outcomes were correlated to the amount of root coverage and gingival thickness gain at 6 months.
Lorenzo Tavelli, Tu Nguyen, Maria Vera Rodriguez, Leonardo Mancini, William V. Giannobile, Shayan Barootchi   +5 more
wiley   +1 more source

Peri‐Implantitis and Soft Tissue Dehiscence in a Turkish Population: Risk Indicators, Diagnostic Parameters and Biomarkers Discovery

Journal of Periodontal Research, EarlyView.
In this Turkish cohort, several risk indicators were identified for peri‐implantitis and peri‐implant soft‐tissue dehiscence. Several PICF immunological markers, particularly IL‐8 and TNF‐α, showed promising diagnostic potential for peri‐implantitis.
Sila Cagri Isler, Gulcin Akca, Berrin Unsal, Georgios Romanos, Anton Sculean, Mario Romandini   +5 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Use of Oncept melanoma vaccine in 69 canine oral malignant melanomas in the United Kingdom [PDF]

, 2017
Bateman, Bergin, Bergman, Bergman, Blackwood, Boria, Bostock, Boston, Brockley, Dank, Esplin, Freeman, Grosenbaugh, Hahn, Harvey, Kosovsky, Liao, Modiano, Murphy, Nguyen, Ottnod, Pires, Proulx, Ramos-Vara, Rassnick, Smedley, Smith, Spangler, Théon, Treggiari, Tuohy, Wallace, Williams   +32 more
core   +3 more sources