Results 31 to 40 of about 16,502 (184)

Large‐Scale Machine Learning to Screen for Small‐Molecule Senolytics

Advanced Intelligent Discovery, EarlyView.
A consistent workflow underpins all experiments in this study. A dedicated model‐selection dataset first identifies optimal hyperparameters for each algorithm. Models are then trained and rigorously evaluated on independent sets of molecules using the senolytic ratio SR. Comprehensive hyperparameter exploration across SMILES representations, task types,
Alexis Dougha, Jesus Gil, Pedro J. Ballester   +2 more
wiley   +1 more source

Constructing a global human epidemic database using open-source digital biosurveillance

Scientific Data
We developed a dataset consisting of outbreak data collected from official, open-source surveillance reports representing more than 170 pathogens, 237 countries and territories, and more than 3300 events that occurred primarily between 1963 and 2023 ...
Rinette Badker, Naama Kipperman, Benjamin Ash, Nita K. Madhav, Ben Oppenheim, Patrick Savage, Nicole Stephenson, Chris Pardee   +7 more
doaj   +1 more source

Comprehensive Characterization of Acer truncatum Leaf Extract: Identification of Systemic Metabolites and Effects on Performance, Antioxidant Status, and Intestinal Microbiota in Laying Hens

Animal Research and One Health, EarlyView.
Dietary A. truncatum leaf extract is absorbed and improves laying performance in aged hens by enhancing systemic antioxidant capacity and modulating the gut microbiota. ABSTRACT The demand for natural feed additives is considerably increasing in the antibiotic‐free feed era.
Kailong Qin, Jiantao Yang, Minglu Gao, Xiaozhao Tao, Xin Yang, Yanli Liu, Xiaojun Yang   +6 more
wiley   +1 more source

Establishing a European wastewater pathogen monitoring network employing aviation samples: a proof of concept

Human Genomics
Pathogens know no borders, and the COVID-19 pandemic highlighted the urgent need for comparable, globally accessible pathogen data. This paper proposes a European wastewater pathogen monitoring network using aircraft and airport samples as a proof of ...
Robert Morfino, Bernd Manfred Gawlik, Simona Tavazzi, Angela Tessarolo, Ana Burgos Gutierrez, Nita K. Madhav, Jasmine Grimsley, Amy Schierhorn, Andrew Franklin, Marta Vargha, Andrew Engeli, Mitchell Wolfe   +11 more
doaj   +1 more source

Integrating Theory and Practice in Regenerative Supply Chain Management: An Integrative Review and Use‐Case Synthesis

Business Strategy and the Environment, EarlyView.
ABSTRACT This integrative review explores the evolution of sustainability in supply chain management and positions regenerative supply chain within the strong sustainability paradigm. It adopts a transdisciplinary approach, unfolding in two parallel stages.
Abhijeet Tewary, Ratri Parida, Surajit Bag   +2 more
wiley   +1 more source

Sustainable plant‐leaf‐derived carbon dots with deep‐red emission enable 1‐min photodynamic therapy of tumors

FlexMat, EarlyView.
In this study, plant‐derived carbon dots (CDs) were prepared using natural plant leaves as raw materials through solvothermal method. These CDs retain the porphyrin structure from chlorophyll and can simultaneously generate I and II types of reactive oxygen species. A 660 nm laser irradiation for only 1 min can achieve efficient photodynamic anti‐tumor
Renjing Chen, Danjie Han, Zemin Wang, Xinyi Lu, Peng He, Lili Hou, Chuantong Cheng, Xueting Liu, Jinli Liu, Zhiming Wang, Zongwen Liu, Xingtao Zhou, Zichao Luo, Kebin Lin   +13 more
wiley   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Main Components and Functional Activities of Ginkgo biloba

Shipin gongye ke-ji, 2022
China is one of the main producing areas of Ginkgo biloba, which resources are quite rich. Its edible and medicinal values are also huge. To make more accurate use of Ginkgo biloba resources with the characteristic of "homology of medicine and food" for ...
Ping WU, Fang YAO, Xingpu QI, Ping LIU, Haibo WANG, Jiaman XU, Haisong ZHENG   +6 more
doaj   +1 more source

Optimizing Hyperbaric Oxygen Therapy for Sudden Hearing Loss

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To optimize the hyperbaric oxygen therapy protocol for sudden sensorineural hearing loss by identifying the most effective treatment course and analyzing key prognostic factors through a multicenter retrospective cohort study. Study Design Retrospective cohort study.
Yuting Sun, Yu Yang, Zhentao Wang, Hui Zhao, Xiaoli Ge, Shuming Pan   +5 more
wiley   +1 more source

Neuroprotective, Anti-Hyperpigmentation, and Anti-Diabetic Effects and Bioaccessibility of Flavonoids in Ginkgo Leaf Infusions from Green and Yellow Leaves

Applied Sciences
Ginkgo (Ginkgo biloba L.) is a widely used medicinal plant, with its green spring leaves commonly utilized for preparing extracts with various therapeutic properties, and leaf infusions also frequently employed.
Iva Jurčević Šangut, Ivana Šola, Dunja Šamec   +2 more
doaj   +1 more source