Results 201 to 210 of about 111,668 (344)

Targeting Regulation of Macrophage to Treat Metabolic Disease: Role of Phytochemicals

open access: yesCell Proliferation, Volume 58, Issue 7, July 2025.
One‐third of the world's population is affected by metabolic syndrome. Complicated pathogenesis and limited drugs cause the growing prevalence of metabolic syndrome. Macrophage‐mediated metaflammation is closely associated with the development of metabolic syndrome. The role of phytochemicals targeting macrophages in the treatment of metabolic syndrome
Zeting Ye   +6 more
wiley   +1 more source

The Sunrise of Tertiary Lymphoid Structures in Cancer

open access: yesImmunological Reviews, Volume 332, Issue 1, July 2025.
ABSTRACT First considered as a negative epiphenomenon in autoimmune and inflammatory diseases, with possible deleterious consequences through the production of pathological autoantibodies and antiself T cells, tertiary lymphoid structures (TLS) have gained major scientific and clinical interest in cancer due to their association with better clinical ...
Juliette Rochefort   +3 more
wiley   +1 more source

P‐Coumaric Acid Improves Skeletal Muscle Atrophy in Chronic Kidney Disease by Modulating TLR4/MyD88/NF‐κB‐Mediated Inflammation and Oxidative Stress

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 14, July 2025.
ABSTRACT Skeletal muscle atrophy is a prevalent complication in chronic kidney disease (CKD), and its pathogenesis is closely related to inflammation and oxidative stress. P‐Coumaric acid (PCA) is a phenolic acid with anti‐inflammatory and antioxidant pharmacological actions.
Hao Wang   +13 more
wiley   +1 more source

Chemical Studies on Oriental Plant Drugs. XIV. Protopanaxadiol, a Genuine Sapogenin of Ginseng Saponins

open access: bronze, 1966
Shoji Shibata   +5 more
openalex   +2 more sources

Ginsenoside Rb1 Alleviated the AKI to CKD Transition by Targeting VEGFR2

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 14, July 2025.
ABSTRACT The decrease of peritubular capillaries, a pathological feature of acute kidney injury (AKI), is a critical part that promotes the transition of AKI to chronic kidney disease (CKD). Ginsenoside Rb1 (Rb1) has various pharmacological effects on multiple systemic diseases. However, whether Rb1 delays the transition of AKI to CKD and the mechanism
Keying Zhang   +9 more
wiley   +1 more source

Efficacy and Mechanism of Bazi Bushen Capsule on Skin Laxity: A Combination of Clinical and Network Pharmacology Study

open access: yesJournal of Cosmetic Dermatology, Volume 24, Issue 7, July 2025.
ABSTRACT Purpose This study aims to explore the mechanism of Bazi Bushen Capsule (BZBS) in treating skin laxity by combining network pharmacology and clinical research. Methods The active ingredients and potential drug targets of BZBS were obtained from TCMSP, TCMBANK, and SuperTCM databases.
Mo Zhao   +12 more
wiley   +1 more source

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