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MoleculesPanax quinquefolius (PQ) has been widely used in traditional Chinese medicine and functional food. Ginsenosides are the important functional components of PQ. The ginsenosides’ diversity is deeply affected by the processing conditions.
Jiali Fan +4 more
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Journal of Ginseng Research, 2016 Background: Rare ginsenosides in Panax quinquefolius L. have strong bioactivities. The fact that it is hard to obtain large amounts of rare ginsenosides seriously restricts further research on these compounds.
Hua Yao +4 more
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Preparation and pharmacological effects of minor ginsenoside nanoparticles: a review
Frontiers in Pharmacology, 2022 Ginseng (Panax ginseng) is a perennial herbaceous plant belonging to Panax genus of Araliaceae. Ginsenosides are a kind of important compounds in ginseng and minor ginsenosides are secondary metabolic derivatives of ginsenosides.
Yue Ke +6 more
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Functional roles and mechanisms of ginsenosides from Panax ginseng in atherosclerosis
Journal of Ginseng Research, 2020 Atherosclerosis (AS) is a leading cause of cardiovascular diseases (CVDs) and it results in a high rate of death worldwide, with an increased prevalence with age despite advances in lifestyle management and drug therapy.
Qianqian Xue +9 more
semanticscholar +1 more source
Micro-/nano-sized delivery systems of ginsenosides for improved systemic bioavailability
Journal of Ginseng Research, 2018 Ginsenosides, dammarane-type triterpene saponins obtained from ginseng, have been used as a natural medicine for many years in the Orient due to their various pharmacological activities. However, the therapeutic potential of ginsenosides has been largely
Hyeongmin Kim +10 more
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Progress on the Studies of the Key Enzymes of Ginsenoside Biosynthesis
Molecules, 2018 As the main bioactive constituents of Panax species, ginsenosides possess a wide range of notable medicinal effects such as anti-cancer, anti-oxidative, antiaging, anti-inflammatory, anti-apoptotic and neuroprotective activities.
Jin-Ling Yang +5 more
doaj +1 more source
Journal of Analytical Methods in Chemistry, 2020 Ultrahigh-performance liquid chromatography Quadrupole-Orbitrap tandem mass spectrometry (UHPLC-Q-Orbitrap-MS/MS) was used to compare the composition of ginsenosides in white ginseng (WG) and extruded white ginseng (EWG).
Yun-Long Guo +9 more
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Ginsenosides analysis of New Zealand–grown forest Panax ginseng by LC-QTOF-MS/MS
Journal of Ginseng Research, 2020 Background: Ginsenosides are the unique and bioactive components in ginseng. Ginsenosides are affected by the growing environment and conditions. In New Zealand (NZ), Panax ginseng Meyer (P.
Wei Chen +2 more
doaj +1 more source
Effect of Lactic Acid Bacteria on the Pharmacokinetics and Metabolism of Ginsenosides in Mice
Pharmaceutics, 2021 This study aims to investigate the effect of lactic acid bacteria (LAB) on in vitro and in vivo metabolism and the pharmacokinetics of ginsenosides in mice.
Ji-Hyeon Jeon +5 more
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source