Results 1 to 10 of about 38,169 (285)

Improvement of Memory in Mice and Increase of Hippocampal Excitability in Rats by Ginsenoside Rg1’s Metabolites Ginsenoside Rh1 and Protopanaxatriol

Journal of Pharmacological Sciences, 2009
Ginsenoside Rg1 has been reported to improve cognitive function in many memory-impaired animal models. However, little is known about the bioactivity of its metabolites in the central nervous system in vivo.
Nai-Hong Chen, Jun-Tian Zhang
exaly   +4 more sources

Anti-Angiogenic Properties of Ginsenoside Rg3

Molecules, 2020
Ginsenoside Rg3 (Rg3) is a member of the ginsenoside family of chemicals extracted from Panax ginseng. Like other ginsenosides, Rg3 has two epimers: 20(S)-ginsenoside Rg3 (SRg3) and 20(R)-ginsenoside Rg3 (RRg3).
Jennifer Hardingham, Timothy Price, Maryam Nakhjavani   +2 more
exaly   +4 more sources

Ginsenoside Rd attenuated hyperglycemia via Akt pathway and modulated gut microbiota in streptozotocin-induced diabetic rats

Current Research in Food Science, 2023
Ginsenoside Rd is a protopanaxadiol abundant in Panax ginseng and Panax notoginseng. It has been reported that ginsenoside Rd possesses various health benefits, such as anti-diabetic, anti-tumor and anti-inflammatory.
Wei Wang, Fengtao Guan, Gianni Sagratini, Jie Yan, Jiahan Xie, Zhibo Jin, Meihong Liu, Huimin Liu, Jingsheng Liu   +8 more
doaj   +2 more sources

Ginsenoside CK, rather than Rb1, possesses potential chemopreventive activities in human gastric cancer via regulating PI3K/AKT/NF-κB signal pathway

Frontiers in Pharmacology, 2022
Ginsenoside Rb1, a main component of ginseng, is often transformed into ginsenoside CK by intestinal flora to exert various pharmacological activity. However, it remains unclear whether ginsenoside CK is responsible for the anti-gastric cancer effect of ...
Yan Wan, Dong Liu, Jia Xia, Jin-Feng Xu, Li Zhang, Yu Yang, Jiao-Jiao Wu, Hui Ao, Hui Ao   +8 more
doaj   +2 more sources

The osteogenesis of Ginsenoside Rb1 incorporated silk/micro-nano hydroxyapatite/sodium alginate composite scaffolds for calvarial defect

International Journal of Oral Science, 2022
Ginsenoside Rb1, the effective constituent of ginseng, has been demonstrated to play favorable roles in improving the immunity system. However, there is little study on the osteogenesis and angiogenesis effect of Ginsenoside Rb1.
Yuqiong Wu, Jiahui Du, Qianju Wu, Ao Zheng, Lingyan Cao, Xinquan Jiang   +5 more
doaj   +2 more sources

Evaluation of glucosidases of Aspergillus niger strain comparing with other glucosidases in transformation of ginsenoside Rb1 to ginsenosides Rg3

Journal of Ginseng Research, 2014
The transformation of ginsenoside Rb1 into a specific minor ginsenoside using Aspergillus niger KCCM 11239, as well as the identification of the transformed products and the pathway via thin layer chromatography and high performance liquid chromatography
Hyun-Dong Paik, Kee-Tae Kim
exaly   +3 more sources

Ginsenoside Rg3 ameliorates allergic airway inflammation and oxidative stress in mice

Journal of Ginseng Research, 2021
Background: Ginsenoside Rg3, isolated from Panax ginseng, has anti-inflammatory and anti-tumor activities. It is known to reduce inflammation in acute lung injury in mice, and to reduce the expression of inflammatory cytokines and COX-2 in human ...
Wen-Chung Huang, Tse-Hung Huang, Kuo-Wei Yeh, Ya-Ling Chen, Szu-Chuan Shen, Chian-Jiun Liou   +5 more
doaj   +2 more sources

Ginsenoside Rb1 Protects Against Diabetic Cardiomyopathy by Regulating the Adipocytokine Pathway

Journal of Inflammation Research, 2022
Chenyang Zhang,1 Meixin Han,2 Xuelian Zhang,1 Hongna Tong,1 Xiaobo Sun,1 Guibo Sun1 1Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, People’s Republic of China; 2College of Pharmacy,
Zhang C, Han M, Zhang X, Tong H, Sun X, Sun G   +5 more
doaj   +2 more sources

Evaluation of ginsenoside bioconversion of lactic acid bacteria isolated from kimchi

Journal of Ginseng Research, 2017
Background: Panax ginseng is a physiologically active plant widely used in traditional medicine that is characterized by the presence of ginsenosides. Rb1, a major ginsenoside, is used as the starting material for producing ginsenoside derivatives with ...
Jong-Hee Lee, Se Hee Lee, Hae Woong Park   +2 more
exaly   +3 more sources

Ginsenoside Rk3 is a novel PI3K/AKT-targeting therapeutics agent that regulates autophagy and apoptosis in hepatocellular carcinoma

Journal of Pharmaceutical Analysis, 2023
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide. Ginsenoside Rk3, an important and rare saponin in heat-treated ginseng, is generated from Rg1 and has a smaller molecular weight.
Lin-Lin Qu, Yan-Nan Liu, Jianjun Deng, Xiao-Xuan Ma, Daidi Fan   +4 more
semanticscholar   +1 more source