Results 31 to 40 of about 27,325 (238)

Analysis of Ginsenosides Rb1 and Rg1 Digestion Products in vitro Based on UHPLC-TSQ MS

Zhipu Xuebao
A method of ultra-high-performance liquid chromatography-triple quadrupole mass spectrometry (UHPLC-TSQ MS) was used to study the products of protopanaxadiol ginsenoside Rb1 and protopanaxatriol ginsenoside Rg1 in simulated digestion solution in vitro ...
Hua-zhou NIU, Yu-xin GUO, Ting ZHOU, Hui LI, Wei WU   +4 more
doaj   +1 more source

Kinetic study for the optimization of ginsenoside Rg3 production by heat treatment of ginsenoside Rb1

Journal of Ginseng Research, 2015
Background: Ginsenoside Rg3 is a promising anticancer agent. It is usually produced by heat treatment of ginseng, in which ginsenoside Rb1 is the major ginsenoside.
Hoang Tung Vo, Jae Youl Cho, Yong-Eui Choi, Yong-Soon Choi, Yeon-Ho Jeong   +4 more
doaj   +1 more source

Ginsenoside Rh2 inhibits breast cancer cell growth viaERβ-TNFα pathway

Acta Biochimica et Biophysica Sinica, 2022
Ginsenoside Rh2 is one of rare panaxidiols extracted from Panax ginseng and a potential estrogen receptor ligand that exhibits moderate estrogenic activity.
Peng Kunjian, Luo Tiao, Li Jijia, Huang Jingjia, Dong Zizeng, Liu Jia, Pi Chaoqiong, Zou Zizeng, Gu Qin, Liu Ousheng, Zhang Jian-Ting, Luo Zhi-Yong   +11 more
doaj   +1 more source

Ginsenoside Rc Ameliorates Endothelial Insulin Resistance via Upregulation of Angiotensin-Converting Enzyme 2

Frontiers in Pharmacology, 2021
Type 2 diabetes mellitus (T2DM) is a major health concern which may cause cardiovascular complications. Insulin resistance (IR), regarded as a hallmark of T2DM, is characterized by endothelial dysfunction.
Yaozhen Wang, Wenwen Fu, Yan Xue, Yan Xue, Zeyuan Lu, Yuangeng Li, Ping Yu, Xiaofeng Yu, Huali Xu, Dayun Sui   +9 more
doaj   +1 more source

Studies on saponin production in tropical medicinal plants Maesa argentea and Maesa lanceolata [PDF]

, 2015
The continuous need for new compounds with important medicinal activities has lead to the identification and characterization of various plant-derived natural products.
Faizal, Ahmad, Geelen, Danny
core   +2 more sources

Characterization of Paenibacillus sp. MBT213 Isolated from Raw Milk and Its Ability to Convert Ginsenoside Rb1 into Ginsenoside Rd from Panax ginseng

Food Science of Animal Resources, 2017
This study was conducted to isolate and characterize Paenibacillus sp. MBT213 possessing β-glucosidase activity from raw milk, and examine the enzymatic capacity on the hydrolysis of a major ginsenoside (Rb1).
Gereltuya Renchinkhand, Soo Hyun Cho, Magsar Urgamal, Young W Park, Joong Hyeon Nam, Hyung Churl Bae, Gyu Yong Song, Myoung Soo Nam   +7 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Component Analysis of Cultivated Ginseng, Red Ginseng, Cultivated Wild Ginseng, and Red Wild Ginseng Using HPLC Method

Journal of Pharmacopuncture, 2008
Objectives : The aim of this experiment is to provide an differentiation of ginseng, red ginseng, cultivated wild ginseng(CWG), and red wild ginseng(RWG) through component analysis using HPLC(High Performance Liquid Chromatography, hereafter HPLC ...
Jang Ho, Lee, Ki Rok, Kwon, Bae Chun, Cha   +2 more
doaj   +1 more source

AMP-activated protein kinase determines apoptotic sensitivity of cancer cells to ginsenoside-Rh2

Journal of Ginseng Research, 2014
Ginseng saponins exert various important pharmacological effects with regard to the control of many diseases, including cancer. In this study, the anticancer effect of ginsenosides on human cancer cells was investigated and compared.
Min-Jung Kim, Hee Yun, Dong-Hyun Kim, Insug Kang, Wonchae Choe, Sung-Soo Kim, Joohun Ha   +6 more
doaj   +1 more source