Results 41 to 50 of about 38,169 (285)
Evidence-Based Complementary and Alternative Medicine, 2022 Individual differences in ginsenoside pharmacokinetics following ginseng administration in humans are still unclear. We aimed to investigate the pharmacokinetic properties of various ginsenosides, including Rb1, Rg3, Rg5, Rk1, F2, and compound K (CK ...
Hyung-Joong Kim +6 more
semanticscholar +1 more source
Neuroprotective effects of ginsenosides
Acta Neurobiologiae Experimentalis, 2006 Ginseng, the root of the Panax species, is a well-known herbal medicine. Traditionally it has been used in Korea, China and Japan for thousands of years. Nowadays it has become a popular and worldwide known health drug. Current scientific studies demonstrate in vivo and in vitro its beneficial effects in a wide range of pathological conditions such as ...
Wolf-Dieter, Rausch +3 more
openaire +2 more sources
Microbial conversion of major ginsenoside Rb1 to minor ginsenoside Rd by Indian fermented food bacteria [PDF]
, 2011 Ginsenoside Rb1 is the predominant secondary metabolite (saponin) in Panax ginseng. Hydrolysis of the sugar residues in Rb1 yields more pharmaceutically active ginsenosides like Rd, Rg3, F2, Rh2 andC-K.
Senthil, K +5 more
core +1 more source
Artificial Cells, Nanomedicine, and Biotechnology, 2019 Background/Aim Ginsenoside Rg1 exerts a beneficial effect in many kidney diseases. But little work has been done to confirm whether ginsenoside Rg1 could also exert a protective effect on anti-glomerular basement membrane (anti-GBM) glomerular nephritis (
Xiaojuan Guo +3 more
doaj +1 more source
Anti-metastatic Potential of Ginsenoside Rp1, a Novel Ginsenoside Derivative
Biological and Pharmaceutical Bulletin, 2008 Ginsenoside Rp1 (G-Rp1) is a novel ginseng saponin with a chemopreventive action. In this study, we examined the anti-metastatic activities of G-Rp1 using relevant in vitro assays and in vivo metastasis models. Using a U937 cell-cell adhesion assay, we found that exogenously added G-Rp1 down-regulates beta1-integrin (CD29) activation at concentrations ...
Park, Tae Yoon +6 more
openaire +3 more sources
Ginsenoside Re Mitigates 6-Hydroxydopamine-Induced Oxidative Stress through Upregulation of GPX4
Molecules, 2020 Ginsenosides are active components found abundantly in ginseng which has been used as a medicinal herb to modify disease status for thousands of years.
Gyeong Hee Lee +5 more
doaj +1 more source
Network Pharmacology-Based Study on the Mechanism of Ginsenoside Rh2 in Glioma Treatment
Natural Product Communications, 2022 Glioma, originated from the neuroectoderm, is one of the prevalent tumors. It is reported that ginsenoside Rh2, a compound extracted from Panax ginseng, shows pharmacological activity in inhibiting the proliferation and metastasis of glioma cells ...
Xue Wu, Xiujiao Qin, Han Dong
doaj +1 more source
Ginsenoside F1 Protects the Brain against Amyloid Beta-Induced Toxicity by Regulating IDE and NEP
Life, 2022 Ginsenoside F1, the metabolite of Rg1, is one of the most important constituents of Panax ginseng. Although the effects of ginsenosides on amyloid beta (Aβ) aggregation in the brain are known, the role of ginsenoside F1 remains unclear.
Yee-Jin Yun +5 more
doaj +1 more source
Pharmaceutical Biology, 2022 Context Panax ginseng C. A. Meyer (Araliaceae) is a famous Asian medicine. Ginsenoside Rc is a component isolated from Panax ginseng.Objective This study evaluates the effect of ginsenoside Rc on myocardial ischaemic injury.Materials and methods Male ...
Lei Shi +7 more
doaj +1 more source
, 2019 Ginsenoside-Rb1 (Rb1), a major active component of ginseng, has many benefits for cardiovascular disease and diabetes mellitus (DM), but the effect and mechanism on diabetic cardiomyopathy are not clear.
Xiao Zhang (152326) +9 more
core +1 more source