Network Pharmacology-Based Study on the Mechanism of Ginsenoside Rh2 in Glioma Treatment
Glioma, originated from the neuroectoderm, is one of the prevalent tumors. It is reported that ginsenoside Rh2, a compound extracted from Panax ginseng, shows pharmacological activity in inhibiting the proliferation and metastasis of glioma cells ...
Xue Wu, Xiujiao Qin, Han Dong
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Photoluminescent And Self-Assembled Hyaluronic Acid-Zinc Oxide-Ginsenoside Rh2 Nanoparticles And Their Potential Caspase-9 Apoptotic Mechanism Towards Cancer Cell Lines [PDF]
Background: Zinc oxide nanoparticles (ZnO NPs) are used in modern cancer therapy based on their specific target, efficacy, low toxicity and biocompatibility.
Castro-Aceituno, Veronica +8 more
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Panax ginseng C. A. Meyer is a kind of renascent herb that belongs to the genus Panax in the family Araliaceae. It is a traditional Chinese precious herbal medicine with a long history of medicinal use.
Kangyu Wang +13 more
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Mapping a novel positive allosteric modulator binding site in the central vestibule region of human P2X7 [PDF]
P2X7 receptors are important in the regulation of inflammatory responses and immune responses to intracellular pathogens such as Mycobacterium tuberculosis and Toxoplasma gondii.
Angulo, Jesus +4 more
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Ginsenoside Re Mitigates 6-Hydroxydopamine-Induced Oxidative Stress through Upregulation of GPX4
Ginsenosides are active components found abundantly in ginseng which has been used as a medicinal herb to modify disease status for thousands of years.
Gyeong Hee Lee +5 more
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Ginsenoside F1 Protects the Brain against Amyloid Beta-Induced Toxicity by Regulating IDE and NEP
Ginsenoside F1, the metabolite of Rg1, is one of the most important constituents of Panax ginseng. Although the effects of ginsenosides on amyloid beta (Aβ) aggregation in the brain are known, the role of ginsenoside F1 remains unclear.
Yee-Jin Yun +5 more
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Context Panax ginseng C. A. Meyer (Araliaceae) is a famous Asian medicine. Ginsenoside Rc is a component isolated from Panax ginseng.Objective This study evaluates the effect of ginsenoside Rc on myocardial ischaemic injury.Materials and methods Male ...
Lei Shi +7 more
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Snailase Preparation of Ginsenoside M1 from Protopanaxadiol-Type Ginsenoside and Their Protective Effects Against CCl4-Induced Chronic Hepatotoxicity in Mice [PDF]
To investigate the protective effects of protopanaxadiol-type ginsenoside (PDG) and its metabolite ginsenoside M1 (G-M1) on carbon tetrachloride (CCl4)-induced chronic liver injury in ICR mice, we carried out conversion of protopanaxadiol-type ...
Hui Wang +9 more
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Background: Ginsenoside Rf is a ginseng saponin found only in Panax ginseng that affects lipid metabolism. It also has neuroprotective and antiinflammatory properties.
Heewon Song +9 more
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Conversion of Protopanaxadiol Type Saponins to Ginsenoside Rg3 by Lemon
The ability of fresh lemon ( Citrus limon ) to convert protopanaxadiol-type saponins into ginsenoside Rg3 was investigated, and the structures of 20( S )-ginsenoside Rg3 (1) and 20( R )-ginsenoside Rg3 (2) were identified by 1 H NMR and 13 C NMR ...
Cheng-Peng Sun +3 more
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