Results 21 to 30 of about 17,049 (209)

Ginsenoside Rf inhibits cyclooxygenase-2 induction via peroxisome proliferator–activated receptor gamma in A549 cells

open access: yesJournal of Ginseng Research, 2019
Background: Ginsenoside Rf is a ginseng saponin found only in Panax ginseng that affects lipid metabolism. It also has neuroprotective and antiinflammatory properties.
Heewon Song   +9 more
doaj   +1 more source

Analysis of Ginsenosides Rb1 and Rg1 Digestion Products in vitro Based on UHPLC-TSQ MS

open access: yesZhipu Xuebao
A method of ultra-high-performance liquid chromatography-triple quadrupole mass spectrometry (UHPLC-TSQ MS) was used to study the products of protopanaxadiol ginsenoside Rb1 and protopanaxatriol ginsenoside Rg1 in simulated digestion solution in vitro ...
Hua-zhou NIU   +4 more
doaj   +1 more source

Conversion of Protopanaxadiol Type Saponins to Ginsenoside Rg3 by Lemon

open access: yesNatural Product Communications, 2012
The ability of fresh lemon ( Citrus limon ) to convert protopanaxadiol-type saponins into ginsenoside Rg3 was investigated, and the structures of 20( S )-ginsenoside Rg3 (1) and 20( R )-ginsenoside Rg3 (2) were identified by 1 H NMR and 13 C NMR ...
Cheng-Peng Sun   +3 more
doaj   +1 more source

Kinetic study for the optimization of ginsenoside Rg3 production by heat treatment of ginsenoside Rb1

open access: yesJournal of Ginseng Research, 2015
Background: Ginsenoside Rg3 is a promising anticancer agent. It is usually produced by heat treatment of ginseng, in which ginsenoside Rb1 is the major ginsenoside.
Hoang Tung Vo   +4 more
doaj   +1 more source

Ginsenoside Rh2 inhibits breast cancer cell growth viaERβ-TNFα pathway

open access: yesActa Biochimica et Biophysica Sinica, 2022
Ginsenoside Rh2 is one of rare panaxidiols extracted from Panax ginseng and a potential estrogen receptor ligand that exhibits moderate estrogenic activity.
Peng Kunjian   +11 more
doaj   +1 more source

Ginsenoside Rc Ameliorates Endothelial Insulin Resistance via Upregulation of Angiotensin-Converting Enzyme 2

open access: yesFrontiers in Pharmacology, 2021
Type 2 diabetes mellitus (T2DM) is a major health concern which may cause cardiovascular complications. Insulin resistance (IR), regarded as a hallmark of T2DM, is characterized by endothelial dysfunction.
Yaozhen Wang   +9 more
doaj   +1 more source

Progress in the Conversion of Ginsenoside Rb1 into Minor Ginsenosides Using β-Glucosidases

open access: yesFoods, 2023
In recent years, minor ginsenosides have received increasing attention due to their outstanding biological activities, yet they are of extremely low content in wild ginseng. Ginsenoside Rb1, which accounts for 20% of the total ginsenosides, is commonly used as a precursor to produce minor ginsenosides via β-glucosidases.
Hongrong Zhu   +3 more
openaire   +3 more sources

Characterization of Paenibacillus sp. MBT213 Isolated from Raw Milk and Its Ability to Convert Ginsenoside Rb1 into Ginsenoside Rd from Panax ginseng

open access: yesFood Science of Animal Resources, 2017
This study was conducted to isolate and characterize Paenibacillus sp. MBT213 possessing β-glucosidase activity from raw milk, and examine the enzymatic capacity on the hydrolysis of a major ginsenoside (Rb1).
Gereltuya Renchinkhand   +7 more
doaj   +1 more source

Artificial Intelligence‐Driven Network Pharmacology: A Methodological Paradigm Shift Bridging Traditional Wisdom and Modern Science

open access: yesAdvanced Intelligent Discovery, EarlyView.
Artificial intelligence is redefining network pharmacology (NP). By integrating knowledge graph engineering, geometric deep learning, multiomics anchoring, and generative reasoning, AI‐driven NP (AI‐NP) transforms static target mapping into dynamic, predictive modeling.
Cong Wang   +9 more
wiley   +1 more source

Chrysin alleviates pressure overload–induced myocardial remodeling through regulating the PI3K/AKT/NRF2 pathway–mediated oxidative stress response

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In this study, we primarily simulated pathological myocardial remodeling induced by transverse aortic constriction surgery and found significant cardiac hypertrophy and fibrosis, characterized by deteriorated cardiac function. Oxidative stress response is considered as a pivotal pathological process, which contributes to inflammation and apoptosis of ...
Yijia Wang   +12 more
wiley   +1 more source

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