Results 31 to 40 of about 583,866 (306)

Effect of Decaffeinated Green Tea Polyphenols on Body Fat and Precocious Puberty in Obese Girls: A Randomized Controlled Trial

open access: yesFrontiers in Endocrinology, 2021
BackgroundObesity has been reported to be an important contributing factor for precocious puberty, especially in girls. The effect of green tea polyphenols on weight reduction in adult population has been shown, but few related studies have been ...
Luyao Xie   +13 more
doaj   +1 more source

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi   +6 more
wiley   +1 more source

From data to immunity: the role of machine learning in advancing malaria vaccine research: a scoping review

open access: yesTropical Diseases, Travel Medicine and Vaccines
Background Malaria remains a significant global health burden, necessitating the development of effective vaccines. Traditional vaccine development is challenged by the complexity of the Plasmodium parasite and lengthy empirical processes.
Shifan Khanday   +7 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Understanding the Barriers to Girls' School Return: Girls' Voices from the Frontline of the COVID-19 Pandemic in East Africa [PDF]

open access: yes, 2021
From October 2020 - March 2021, AMPLIFY Girls, undertook a multi-country qualitative research study to ask girls why they were dropping out of school and their recommendations to get young women back to school and back on track.The results are painful ...
Aubryn Allyn Sidle   +4 more
core  

SPECIAL ASPECTS OF MOTOR FITNESS INFLUENCE ON LEVEL OF 11-13 YEARS’ AGE GIRLS’ PHYSICAL EXERCISES’ MASTERING

open access: yesPedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2017
Purpose: to find special aspects of motor fitness influence on level of 11-13 years’ age girls’ physical exercises’ mastering. Material: in the research 11 years’ age girls (n=51), 12 years’ age (n=54) and 13 years (n=63) participated.
O.V. Ivashchenko
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Partnership for Girls: Picture This! Photovoice

open access: yes, 2023
The Physical Activity Partnership for Girls was funded by the National Institute on Minority Health and Health Disparities (R24MD005096)."This record includes materials of the Picture This!
Latino Research Institute   +1 more
core   +1 more source

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