Results 51 to 60 of about 861,292 (341)

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Multi-Temporal Analysis and Trends of the Drought Based on MODIS Data in Agricultural Areas, Romania

open access: yesRemote Sensing, 2020
The aim of this study is to analyze the performance of the Drought Severity Index (DSI) in Romania and its validation based on other data sources (meteorological data, soil moisture content (SMC), agricultural production).
Claudiu-Valeriu Angearu   +7 more
doaj   +1 more source

Spatio-temporal distribution of off-shore ships in the Pars Special Economic Energy Zone based on satellite imagery [PDF]

open access: yesEnvironmental Resources Research, 2019
Special Economic Zones (SEZs) are areas controlled by specific legislations so as toattain economic prosperity. These zones are commonly established and controlled bygovernment officials and are primarily characterized by growing population and ...
Qadir Ashournejad   +3 more
doaj   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

Investigation of Timing Behavior and Jitter in a Smart Inertial Sensor Debugging Architecture

open access: yesSensors, 2021
Due to upcoming higher integration levels of microprocessors, the market of inertial sensors has changed in the last few years. Smart inertial sensors are becoming more and more important.
Daniel Gis   +2 more
doaj   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Testing Exhaust Emissions of Plug-In Hybrid Vehicles in Poland

open access: yesEnergies
The article addresses the usage patterns of plug-in hybrid vehicles (PHEVs) under Polish conditions. The conventional approach to operating such vehicles assumes that they are used with a fully charged battery at the start.
Jacek Pielecha, Wojciech Gis
doaj   +1 more source

Conceptions of geographic information systems (GIS) held by senior geography students in Queensland [PDF]

open access: yes, 2008
Geographical Information Systems (GIS) represent one of the major contributions to spatial analysis and planning of the new technologies. While teachers and others have viewed its potential contribution to geographical education as considerable, it has ...
West, Bryan A.
core   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

GIS and Types of GIS Education Programs

open access: yesProcedia - Social and Behavioral Sciences, 2012
AbstractRecent developments in mapping technologies that forms data for planning and decision mechanism, makes it necessary to use these technologies by forming “clever maps” through geographical information systems (GIS). Up to now, the concept of GIS couldn’t be understood both in educational institutions and at private sector.
openaire   +2 more sources

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